User profiles for T. Kasumov
Takhar KasumovNEOMED Verified email at neomed.edu Cited by 4516 |
Role of ceramides in nonalcoholic fatty liver disease
M Pagadala, T Kasumov, AJ McCullough… - Trends in endocrinology …, 2012 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is a chronic disease with a histological spectrum
ranging from steatosis alone, to nonalcoholic steatohepatitis (NASH). The latter is associated …
ranging from steatosis alone, to nonalcoholic steatohepatitis (NASH). The latter is associated …
Mitochondrial redox regulation and myocardial ischemia-reperfusion injury
…, L Zhang, Z Jin, T Kasumov… - American Journal of …, 2022 - journals.physiology.org
Mitochondrial reactive oxygen species (ROS) have emerged as an important mechanism of
disease and redox signaling in the cellular system. Under basal or pathological conditions, …
disease and redox signaling in the cellular system. Under basal or pathological conditions, …
Plasma ceramides are elevated in obese subjects with type 2 diabetes and correlate with the severity of insulin resistance
OBJECTIVE—To quantitate plasma ceramide subspecies concentrations in obese subjects
with type 2 diabetes and relate these plasma levels to the severity of insulin resistance. …
with type 2 diabetes and relate these plasma levels to the severity of insulin resistance. …
[HTML][HTML] Ceramide as a mediator of non-alcoholic fatty liver disease and associated atherosclerosis
Cardiovascular disease (CVD) is a serious comorbidity in nonalcoholic fatty liver disease (NAFLD).
Since plasma ceramides are increased in NAFLD and sphingomyelin, a ceramide …
Since plasma ceramides are increased in NAFLD and sphingomyelin, a ceramide …
Hyperammonaemia‐induced skeletal muscle mitochondrial dysfunction results in cataplerosis and oxidative stress
Key points Hyperammonaemia occurs in hepatic, cardiac and pulmonary diseases with
increased muscle concentration of ammonia. We found that ammonia results in reduced skeletal …
increased muscle concentration of ammonia. We found that ammonia results in reduced skeletal …
Improved insulin sensitivity after exercise training is linked to reduced plasma C 14: 0 ceramide in obesity and type 2 diabetes
T Kasumov, TPJ Solomon, C Hwang, H Huang… - …, 2015 - Wiley Online Library
Improved insulin sensitivity after exercise training is linked to reduced plasma C14:0 ceramide
in obesity and type 2 diabetes - Kasumov - 2015 - Obesity - Wiley Online Library Skip to …
in obesity and type 2 diabetes - Kasumov - 2015 - Obesity - Wiley Online Library Skip to …
[PDF][PDF] Carboxylesterase 2 prevents liver steatosis by modulating lipolysis, endoplasmic reticulum stress, and lipogenesis and is regulated by hepatocyte nuclear factor …
… Statistical significance was analyzed using unpaired Student t test or analysis of variance
(GraphPad Prism; GraphPad Software Inc., La Jolla, CA). All values are expressed as mean 6 …
(GraphPad Prism; GraphPad Software Inc., La Jolla, CA). All values are expressed as mean 6 …
Gastric bypass surgery reduces plasma ceramide subspecies and improves insulin sensitivity in severely obese patients
H Huang, T Kasumov, P Gatmaitan, HM Heneghan… - …, 2011 - Wiley Online Library
Bariatric surgery is associated with near immediate remission of type 2 diabetes and
hyperlipidemia. The mechanisms underlying restoration of normal glucose tolerance …
hyperlipidemia. The mechanisms underlying restoration of normal glucose tolerance …
[HTML][HTML] Reversal of metabolic disorders by pharmacological activation of bile acid receptors TGR5 and FXR
Objectives Activation of the bile acid (BA) receptors farnesoid X receptor (FXR) or G protein-coupled
bile acid receptor (GPBAR1; TGR5) improves metabolic homeostasis. In this study, …
bile acid receptor (GPBAR1; TGR5) improves metabolic homeostasis. In this study, …
Quantification of ceramide species in biological samples by liquid chromatography electrospray ionization tandem mass spectrometry
T Kasumov, H Huang, YM Chung, R Zhang… - Analytical …, 2010 - Elsevier
We present an optimized and validated liquid chromatography electrospray ionization
tandem mass spectrometry (LC–ESI–MS/MS) method for the simultaneous measurement of …
tandem mass spectrometry (LC–ESI–MS/MS) method for the simultaneous measurement of …