User profiles for Tadeja Režen
 | Tadeja Reženassoc. prof. of Biochemistry, University of Ljubljana, Faculty of Medicine Verified email at mf.uni-lj.si Cited by 1109 |
[HTML][HTML] The role of bile acids in carcinogenesis
Bile acids are soluble derivatives of cholesterol produced in the liver that subsequently
undergo bacterial transformation yielding a diverse array of metabolites. The bulk of bile acid …
undergo bacterial transformation yielding a diverse array of metabolites. The bulk of bile acid …
Cholesterol, lipoproteins, and COVID-19: Basic concepts and clinical applications
Cholesterol is being recognized as a molecule involved in regulating the entry of the SARS-CoV-2
virus into the host cell. However, the data about the possible role of cholesterol …
virus into the host cell. However, the data about the possible role of cholesterol …
Regulation of hepatic cytochromes p450 by lipids and cholesterol
Cytochromes P450 of the liver are involved in maintenance of lipid homeostasis (cholesterol,
vitamin D, oxysterol and bile acid metabolism) and in detoxification processes of …
vitamin D, oxysterol and bile acid metabolism) and in detoxification processes of …
MicroRNA in skeletal muscle development, growth, atrophy, and disease
Micro RNAs (miRNAs) are short noncoding RNAs that are important global‐ as well as tissue‐
and cell‐type‐specific regulators of gene expression. Muscle‐specific miRNAs or myomirs …
and cell‐type‐specific regulators of gene expression. Muscle‐specific miRNAs or myomirs …
[HTML][HTML] Effect of CAR activation on selected metabolic pathways in normal and hyperlipidemic mouse livers
T Režen, V Tamasi, A Lövgren-Sandblom, I Björkhem… - BMC genomics, 2009 - Springer
Background Detoxification in the liver involves activation of nuclear receptors, such as the
constitutive androstane receptor (CAR), which regulate downstream genes of xenobiotic …
constitutive androstane receptor (CAR), which regulate downstream genes of xenobiotic …
[HTML][HTML] Oxysterols and gastrointestinal cancers around the clock
This review focuses on the role of oxidized sterols in three major gastrointestinal cancers (hepatocellular
carcinoma, pancreatic, and colon cancer) and how the circadian clock affects …
carcinoma, pancreatic, and colon cancer) and how the circadian clock affects …
Network and systems medicine: Position paper of the european collaboration on science and technology action on open multiscale systems medicine
…, E Pujos-Guillot, T Režen… - Network and systems …, 2020 - liebertpub.com
Introduction: Network and systems medicine has rapidly evolved over the past decade, thanks
to computational and integrative tools, which stem in part from systems biology. However, …
to computational and integrative tools, which stem in part from systems biology. However, …
Acrolein consumption induces systemic dyslipidemia and lipoprotein modification
…, OA Barski, JF Lesgards, P Juvan, T Rezen… - Toxicology and applied …, 2010 - Elsevier
Aldehydes such as acrolein are ubiquitous pollutants present in automobile exhaust, cigarette,
wood, and coal smoke. Such aldehydes are also constituents of several food substances …
wood, and coal smoke. Such aldehydes are also constituents of several food substances …
[HTML][HTML] Circular RNA hsa_circ_0062682 binds to YBX1 and promotes oncogenesis in Hepatocellular Carcinoma
Simple Summary Circular RNA (circRNA) have a role in carcinogenesis in different cancers,
also in hepatocellular carcinoma (HCC). The transcriptome analyses of HCC tumours …
also in hepatocellular carcinoma (HCC). The transcriptome analyses of HCC tumours …
[HTML][HTML] Identification of variants associated with rare hematological disorder erythrocytosis using targeted next-generation sequencing analysis
An erythrocytosis is present when the red blood cell mass is increased, demonstrated as
elevated hemoglobin and hematocrit in the laboratory evaluation. Congenital predispositions …
elevated hemoglobin and hematocrit in the laboratory evaluation. Congenital predispositions …