Induction of rat hepatic cytochrome P450 2B subfamily by azidophenobarbital, as a possible photoaffinity probe for the putative phenobarbital receptor: comparative …

T Shinohara, K Taura, T Imamura, H Yamada… - Drug metabolism and …, 1997 - ASPET
To study the specific target to which phenobarbital (PB) binds, resulting in the induction of
cytochrome P450, we prepared two azido-PBs (AZPBs) as photoaffinity ligands. The azido …

[PDF][PDF] Aerodynamic noise produced in flow around an automobile bonnet

H Yokoyama, T Nakajima, T Shinohara… - INTER-NOISE and …, 2014 - acoustics.asn.au
To clarify the mechanism and conditions of the intense acoustic radiation from flows around
a curvilinear body with a kink shape in an accelerated boundary layer, the experiments were …

FACTORS INVOLVED IN THE INDUCTION OF THE CYP2B SUBFAMILY P450: SEARCH FOR THE TARGET OF INDUCERS USING PHOTOAFFINITY PROBE AND …

…, Y MATSUKI, E FUKUDA, T SHINOHARA… - Drug Metabolism and …, 1999 - jstage.jst.go.jp
To clarify the mechanism of phenobarbital-mediated increase in the CYP2B subfamily, we
tried to detect target (s) of the inducer using azido-PB (AZPB), a photoaffinity ligand, as the …

Characteristics of non-culprit plaques in acute coronary syndrome patients with layered culprit plaque

…, O Kurihara, M Araki, H Shinohara… - European Heart …, 2020 - academic.oup.com
Aims Layered plaques represent signs of previous plaque destabilization. A recent study
showed that acute coronary syndrome (ACS) patients with layered culprit plaque have more …

Relationships among high school student-athletes' mental health, stressors, and social support during the COVID-19 pandemic in Japan

K Yamaguchi, E Katagami, R Shinohara, T Tsuji… - medRxiv, 2021 - medrxiv.org
Objectives The impact of the spread of COVID-19 on the mental health and its mitigating
factors of high school athletes is not fully understood. The aims of this study were 1) to describe …

DPP (Dipeptidyl Peptidase)-4 inhibitor attenuates ang II (Angiotensin II)–induced cardiac hypertrophy via GLP (Glucagon-Like Peptide)-1–dependent suppression of …

…, T Yamamoto, M Sada, H Deguchi, K Shinohara… - …, 2020 - Am Heart Assoc
Nox4 (NADPH [Nicotinamide adenine dinucleotide phosphate] oxidase 4) is a major source
of oxidative stress and is intimately involved in cardiac hypertrophy. DPP (Dipeptidyl …

Conductivity and Field Effect Transistor of La2@C80 Metallofullerene

…, A Fujiwara, A Taninaka, H Shinohara… - Journal of the …, 2003 - ACS Publications
We first demonstrate a field-effect-transistor operation of dimetallofullerene La 2 @C 80 with
the icosahedral cage symmetry. The thin-film device showed an n-type behavior with a …

Gut microbiota influence the development of abdominal aortic aneurysm by suppressing macrophage accumulation in mice

R Shinohara, H Nakashima, T Emoto, T Yamashita… - …, 2022 - Am Heart Assoc
Background: Abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease
characterized by dilated abdominal aorta. Immune cells have been shown to contribute to …

Application studies on effective use of f-elements

…, T Kobayashi, T Uda, S Yamanaka, A Shinohara… - 2014 - osti.gov
As for the studies on actinides and lanthanides, with a core on the project study of Kyoto
University Research Reactor Institute, f-element application projects are promoted all over Japan…

Healed plaques in patients with stable angina pectoris

…, V Thondapu, M Araki, H Shinohara… - … and Vascular Biology, 2020 - Am Heart Assoc
Objective: Healed plaques, signs of previous plaque destabilization, are frequently found in
the coronary arteries. Healed plaques can now be diagnosed in living patients. We …