… and is potentially a route for their delivery as nanoparticles. The skin provides a natural
physical … In this review we discuss the skin as a nanoparticle barrier, recent work in the field of …

… by diffusion across a semi-permeable membrane. In vivo, this process is accomplished by
constantly perfusing the microdialysis probe with a physiological solution at a low flow rate. …

… a commonly utilized dosing strategy to minimize toxicity and maximize the efficacy of drugs
with a … (PK) and therefore the optimal dose of a drug for an individual patient are difficult to …

… The results of this study support a need for a large multicentered trial comparing the clinical
and bacteriologic outcomes of continuous infusion and bolus dosing of a β-lactam antibiotic …

… a 2D area and measuring fluorescence at a given tissue depth below the surface after excitation
by a laser beam with a … followed by the stacking together of a series of 2D images from …

There are a growing number of commercial uses of nanoparticles which involve direct people
contact with the potential for absorption through the skin. Nanoparticles are present in a …

Purpose There is a lack of relevant, non-animal alternatives for assessing exposure and
toxicity of nanoparticle-containing cosmetics, eg sunscreens. Our goal was to evaluate …

Background Deliberate self-poisoning with older pesticides such as organophosphorus
compounds are commonly fatal and a serious public health problem in the developing world. …

This study documents drug–excipient incompatibility studies of acyclovir in physical mixtures
with lactose and in different tablet brands. Differential scanning calorimetry (DSC) was …

… The objective of this work was to develop a method for the simultaneous determination of …
Chromatographic separation was achieved on a reversed phase column (C18, 2.6 μm, 2.1 × …