Psoriasis is an inflammatory skin disease with strong neutrophil (PMN) infiltration and high
levels of the antimicrobial peptide, LL37. LL37 in complex with DNA and RNA is thought to …

A<sc>bstract</sc> Human pluripotent stem cells (hPSCs) are a unique source for the, in
principle, unlimited production of functional human cell types in vitro, which are of high value for …

Background There is evidence for a relevant role of inflammation in the pathogenesis of
Parkinson’s disease (PD). Mutations in the LRRK2 gene represent the most frequent genetic …

Inflammation modifies the incidence and progression of Parkinson’s disease (PD). By using
30 inflammatory markers in CSF in 498 people with PD and 67 people with dementia with …

Aberrant signaling through the Wnt/β-catenin pathway is a critical determinant in human
and rodent liver carcinogenesis and generally accepted to be a potent driver of proliferation. …

The first ATP‐competitive p38a MAPK/MAPK14 inhibitor with excellent in vivo efficacy and
selectivity, skepinone‐L, is now available. We investigated the impact of selective p38a MAPK/…

The process of hepatocarcinogenesis in the diethylnitrosamine (DEN) initiation/phenobarbital
(PB) promotion mouse model involves the selective clonal outgrowth of cells harboring …

Background: Blood levels of immune markers have been proposed to discriminate patients
with Parkinson's disease (PD) from controls. However, differences between clinical PD …

The receptor for the hepatocyte growth factor/scatter factor (HGF/SF), c‐Met, plays a role in
tumour promotion, progression and metastasis. In this study, we analysed chemically induced …

Objective Alcoholic hepatitis (AH) is often associated with advanced fibrosis, which negatively
impacts survival. We aimed at identifying kinases deregulated in livers from patients with …