L-Ascorbic acid (AsA) is a water-soluble antioxidant. We examined the effect of AsA deficiency
on skeletal muscle using senescence marker protein-30 (SMP30)-knockout (KO) mice …

Androgens are key regulators that play a critical role in the male reproductive system and
have anabolic effects on bone mineral density and skeletal muscle mass. We have previously …

Background Pregnane X receptor (PXR) is a key regulator of the induction of drug metabolizing
enzymes. PXR has been studied for its importance in drug-drug or herb-drug interactions…

Vancomycin is recommended for treating severe infections caused by Grampositive cocci,
including methicillin-resistant Staphylococcus aureus. However, renal damage often occurs …

The constitutive androstane receptor ( CAR , NR 1I3) is very important for drug development
and for understanding pharmacokinetic drug–drug interactions. We screened by …

Recently, selective androgen receptor modulators (SARMs), which bind to AR and act in a
tissue/effect-specific manner, have been developed, but the selective mechanism is not well …

Pregnane X receptor (PXR) is known as a xenosensor, playing a key role in response to
xenochemical stimuli. Activation of PXR enhanced expression of various drug-metabolizing …

An efficient Pd II /Pd 0 -p-benzoquinone/hydroquinone-CuCl 2 /CuCl catalyst system was
developed that uses environmentally friendly molecular oxygen as the terminal oxidant to …

Background: Low plasma ascorbate levels in hemodialysis patients have been reported
worldwide; hence, many end-stage kidney disease patients are forced to restrict their diets, …

Total amount of L‐ascorbic acid (AsA) in human skeletal muscle is approximately 40%. As
satellite cells, muscle specific stem cells, are responsible for providing new myoblast cells …