Impact of intestinal glucuronidation on the pharmacokinetics of raloxifene
…, T Ohtsuka, I Kino, T Tanimoto… - Drug metabolism and …, 2011 - ASPET
Raloxifene is extensively glucuronidated in humans, effectively reducing its oral bioavailability
(2%). It was also reported to be glucuronidated in preclinical animals, but its effects on the …
(2%). It was also reported to be glucuronidated in preclinical animals, but its effects on the …
Stepwise synthesis and characterization of germa [4],[5],[8], and [10] pericyclynes
H Tanimoto, T Nagao, T Fujiwara, Y Nishiyama… - Dalton …, 2015 - pubs.rsc.org
The stepwise syntheses of germa[N]pericyclynes, including [5]pericyclynes, and their
characterization are described. The yields of germa[4] and [8]pericyclynes were improved …
characterization are described. The yields of germa[4] and [8]pericyclynes were improved …
Anomalous elastic properties of amorphous alloys suggesting a collective motion of many atoms
H Mizubayashi, T Usui, H Tanimoto - Journal of non-crystalline solids, 2002 - Elsevier
The Young's modulus, E(ε t ,f), was measured as a function of the strain amplitude, ε t and the
measurement frequency, f, at room temperature for melt-spun amorphous (a-) Pd 80 Si 20 , …
measurement frequency, f, at room temperature for melt-spun amorphous (a-) Pd 80 Si 20 , …
Synthesis and characterization of ethynylated germa [4] pericyclyne
H Tanimoto, T Nagao, S Hosokawa, T Fujiwara… - Chemistry …, 2016 - academic.oup.com
This paper presents the synthesis and characterization of (TMS-ethynyl)-substituted germa[4]pericyclyne
composed of acetylene moieties and germanium atoms. Characterization was …
composed of acetylene moieties and germanium atoms. Characterization was …
Key determinants of the circulatory exposure of organic anions: differences in hepatic uptake between multidrug resistance-associated protein 2 (Mrp2)-deficient rats …
K Kosaka, T Watanabe, T Susukida, S Aoki, S Sekine… - Xenobiotica, 2015 - Taylor & Francis
Full article: Key determinants of the circulatory exposure of organic anions: differences in
hepatic uptake between multidrug resistance-associated protein 2 (Mrp2)-deficient rats and wild…
hepatic uptake between multidrug resistance-associated protein 2 (Mrp2)-deficient rats and wild…
Utility of bilirubins and bile acids as endogenous biomarkers for the inhibition of hepatic transporters
T Watanabe, M Miyake, T Shimizu, M Kamezawa… - Drug Metabolism and …, 2015 - ASPET
It is useful to identify endogenous substrates for the evaluation of drug-drug interactions via
transporters. In this study, we investigated the utility of bilirubins, substrates of OATPs and …
transporters. In this study, we investigated the utility of bilirubins, substrates of OATPs and …
[HTML][HTML] Phenotypic and functional properties of dedifferentiated fat cells derived from infrapatellar fat pad
K Tanimoto, T Matsumoto, Y Nagaoka, T Kazama… - Regenerative …, 2022 - Elsevier
Introduction Mature adipocyte-derived dedifferentiated fat cells (DFATs) are mesenchymal
stem cell (MSC)-like cells with high proliferative ability and multilineage differentiation …
stem cell (MSC)-like cells with high proliferative ability and multilineage differentiation …
Marginal and Scalar Solutions in Cubic Open String Field Theory
T Tomohiko, T Seriko - 2002 - arch.neicon.ru
We find marginal and scalar solutions in cubic open string field theory by using left-right
splitting properties of a delta function. The marginal solution represents a marginal deformation …
splitting properties of a delta function. The marginal solution represents a marginal deformation …
Synthesis and characterization of germa [n] pericyclynes
H Tanimoto, T Nagao, Y Nishiyama, T Morimoto… - Dalton …, 2014 - pubs.rsc.org
The synthesis and characterization of novel pericyclynes comprising germanium atoms and
acetylenes, germa[n]pericyclynes, are described. The prepared germa[4]-, [6]-, and [8]…
acetylenes, germa[n]pericyclynes, are described. The prepared germa[4]-, [6]-, and [8]…
Extended germa [N] pericyclynes: synthesis and characterization
H Tanimoto, T Fujiwara, J Mori, T Nagao… - Dalton …, 2017 - pubs.rsc.org
We herein describe the syntheses and characterization of extended germa[N]pericyclynes,
which are macrocycles composed of germanium–butadiyne units. The obtained novel …
which are macrocycles composed of germanium–butadiyne units. The obtained novel …