User profiles for Tsutomu Nakamura

Tsutomu Nakamura

The University of Tokyo
Verified email at iqb.u-tokyo.ac.jp
Cited by 2604

A randomized trial comparing postoperative adjuvant chemotherapy with cisplatin and 5-fluorouracil versus preoperative chemotherapy for localized advanced …

…, M Shinoda, S Ozawa, H Shimizu, T Nakamura… - Annals of surgical …, 2012 - Springer
Background Patients with esophageal carcinoma receiving postoperative chemotherapy
showed superior disease-free survival than those receiving surgery alone in a Japan Clinical …

Axin, an inhibitor of the Wnt signalling pathway, interacts with β‐catenin, GSK‐3β and APC and reduces the β‐catenin level

T Nakamura, F Hamada, T Ishidate, K Anai… - Genes to …, 1998 - Wiley Online Library
Background: The Wnt/Wingless signalling pathway plays an important role in both embryonic
development and tumorigenesis. β‐Catenin and Axin are positive and negative effectors of …

Inhibition of Wnt signaling by ICAT, a novel β-catenin-interacting protein

K Tago, T Nakamura, M Nishita, J Hyodo… - Genes & …, 2000 - genesdev.cshlp.org
Wnt signaling has an important role in both embryonic development and tumorigenesis. β-Catenin,
a key component of the Wnt signaling pathway, interacts with the TCF/LEF family of …

[HTML][HTML] Possible relationship of monocyte chemoattractant protein-1 with diabetic nephropathy

N Banba, T Nakamura, M Matsumura, H Kuroda… - Kidney international, 2000 - Elsevier
… Author links open overlay panel Nobuyuki Banba , Tsutomu Nakamura , Michiko
Matsumura , Hisamoto Kuroda , Yoshiyuki Hattori , Kikuo Kasai …

MDR1 genotype-related pharmacokinetics of digoxin after single oral administration in healthy Japanese subjects

T Sakaeda, T Nakamura, M Horinouchi… - Pharmaceutical …, 2001 - Springer
Purpose. To evaluate the MDR1 genotype frequency in the Japanese population and to
study the relationship between the MDR1 genotype and the pharmacokinetics of digoxin after …

Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus

Y Oomura, H Ooyama, M Sugimori, T Nakamura… - Nature, 1974 - nature.com
IT is generally accepted that the lateral hypothalamic area (LH) and ventromedial nucleus (VMH)
have a reciprocal relationship in the control of feeding behaviour 1–3 , and that some …

Precipitation and atmospheric circulation patterns at mid‐latitudes of Asia

…, VB Aizen, JM Melack, T Nakamura… - … of Climatology: A …, 2001 - Wiley Online Library
Analyses of the coupling between large‐scale atmospheric patterns and modifications of
regional precipitation regimes at seasonal and annual time scales in different terrain of mid‐…

Effect of the mutation (C3435T) at exon 26 of the MDR1 gene on expression level of MDR1 messenger ribonucleic acid in duodenal enterocytes of healthy Japanese …

T Nakamura, T Sakaeda, M Horinouchi… - Clinical …, 2002 - Wiley Online Library
The effect of the C3435T mutation at exon 26 of the MDR1 gene on the expression levels of
MDR1 messenger ribonucleic acid (mRNA) was evaluated by means of real‐time …

Pharmacogenetics of MDR1 and its impact on the pharmacokinetics and pharmacodynamics of drugs

T Sakaeda, T Nakamura, K Okumura - Pharmacogenomics, 2003 - Taylor & Francis
The multi-drug resistant transporter MDR1/P-glycoprotein, the gene product of MDR1, is a
glycosylated membrane protein of 170 kDa, belonging to the ATP-binding cassette (ABC) …

Climate change and extension of the Ginkgo biloba L. growing season in Japan

…, T Ohta, M Irasawa, T Nakamura - Global Change …, 2003 - Wiley Online Library
To understand the effects of climate change on the growing season of plants in Japan, we
conducted trend analysis of phenological phases and examined the relationship between …