The inhibitory effects of silymarin, its main constituent silibinin and the metabolite silibinin-glucuronide
on UDP-glucuronosiltransferase (UGT) were evaluated in rat hepatic microsomes. …

Ethinylestradiol (EE) induces cholestasis by affecting bile salt-dependent and -independent
fractions of the bile flow. The decrease in bile salt-independent flow is thought to be due, in …

Original research: hMENA isoforms regulate cancer intrinsic type I IFN signaling and extrinsic
mechanisms of resistance to immune checkpoint blockade in NSCLC - PMC Back to Top …

High-grade B cell lymphomas with concurrent activation of the MYC and BCL2 oncogenes,
also known as double-hit lymphomas (DHL), show dismal prognosis with current therapies. …

Agricultural production is sensitive to weather and thus directly affected by climate change.
In Argentina, the geographic region known as the “Pampa” is at the heart of agricultural …

Aquaculture accounts for almost one-half of global fish consumption. Understanding the
regional impact of climate fluctuations on aquaculture production thus is critical for the …

Our mission is to create an international platform for experts engaged in the field of
Christian mission and missiology, charity, social and humanitarian development work at the …

… in more recent periods (1984–2014) (D’Andrea et al. 2019) agree with our results. …
Penman–Monteith formulation) and PP were documented by D’Andrea et al. (2019) in …

206 Contributors in urban energy landscapes. She has recently completed projects on
participatory urban planning for climate change in East Africa and on the energy landscapes of …

Although many genotoxic treatments upregulate the cyclin kinase inhibitor p21, agents such
as UV irradiation trigger p21 degradation. This suggests that p21 blocks a process relevant …