[HTML][HTML] Genetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cells
V González-Pérez, DJ Reiner, JK Alan… - Journal of Molecular …, 2010 - Springer
Background Activation of the mammalian Ras-Raf-MEK-ERK MAPK signaling cascade
promotes cellular proliferation, and activating Ras mutations are implicated in cancer onset and …
promotes cellular proliferation, and activating Ras mutations are implicated in cancer onset and …
Selection of priority natural products for evaluation as potential precipitants of natural product–drug interactions: a NaPDI center recommended approach
EJ Johnson, V González-Peréz, DD Tian, YS Lin… - Drug Metabolism and …, 2018 - ASPET
Pharmacokinetic interactions between natural products (NPs) and conventional medications
(prescription and nonprescription) are a longstanding but understudied problem in …
(prescription and nonprescription) are a longstanding but understudied problem in …
Use of Caenorhabditis elegans to evaluate inhibitors of Ras function in vivo
The human RAS genes constitute the most frequently mutated oncogenes in human cancers,
and the critical role of aberrant Ras protein function in oncogenesis is well established. …
and the critical role of aberrant Ras protein function in oncogenesis is well established. …
Impact of organic solvents on cytochrome P450 probe reactions: filling the gap with (S)-Warfarin and midazolam hydroxylation
V Gonzalez-Perez, EA Connolly, AS Bridges… - Drug metabolism and …, 2012 - ASPET
(S)-Warfarin 7-hydroxylation and midazolam 1′-hydroxylation are among the preferred
probe substrate reactions for CYP2C9 and CYP3A4/5, respectively. The impact of solvents on …
probe substrate reactions for CYP2C9 and CYP3A4/5, respectively. The impact of solvents on …
Indinavir increases midazolam N-glucuronidation in humans: identification of an alternate CYP3A inhibitor using an in vitro to in vivo approach
…, C Leonowens, EJ Cox, V González-Pérez… - Drug Metabolism and …, 2019 - ASPET
Midazolam is a widely used index substrate for assessing effects of xenobiotics on CYP3A
activity. A previous study involving human hepatocytes showed the primary route of …
activity. A previous study involving human hepatocytes showed the primary route of …
Tierra de aguas mansas: procesos de minería y urbanización sensibles al agua: estrategias para adaptar los procesos de minería y urbanización en un territorio …
V González Pérez, L Jaramillo Orrego… - 2019 - lareferencia.info
Tierra de aguas mansas estudia un territorio estratégico que presta importantes servicios
ecosistémicos (SE) y que están siendo presionados por motores de cambio. La motivación …
ecosistémicos (SE) y que están siendo presionados por motores de cambio. La motivación …
Engineering threshold-based selection systems
KH Pedone, V González-Pérez, LE Leopold… - G3, 2021 - academic.oup.com
Using model organisms to identify novel therapeutic targets is frequently constrained by pre-existing
genetic toolkits. To expedite positive selection for identification of novel downstream …
genetic toolkits. To expedite positive selection for identification of novel downstream …
[PDF][PDF] Transcripción tematizada
V González Pérez, D Román-Odio - 2019 - digital.kenyon.edu
Vanessa González [00: 01: 26] Bueno, sobre el Espiritismo aprendí a través de mi padre.
Eso fue lo que yo creí en un comienzo porque él buscó mayor conocimiento desde yo muy, …
Eso fue lo que yo creí en un comienzo porque él buscó mayor conocimiento desde yo muy, …
[PDF][PDF] Indexed Interview
V González Pérez - 2019 - digital.kenyon.edu
Vanessa González [00: 01: 26] Well, I learned about Spiritism through my father. That is what
I believed in the beginning. I say this because since I was very young he sought knowledge …
I believed in the beginning. I say this because since I was very young he sought knowledge …
Determining the Fraction Unbound of Herbal Product Constituents in Human Liver Microsomes to Improve Herb‐Drug Interaction Predictions
D Armstrong, B Gufford, V Gonzalez‐Perez… - The FASEB …, 2015 - Wiley Online Library
Adverse interactions between herbal products and conventional medications are a growing
public health concern. Inhibition of drug metabolizing enzyme activity by herbal constituents …
public health concern. Inhibition of drug metabolizing enzyme activity by herbal constituents …