The human cytochromes P450 (P450) CYP3A contribute to the biotransformation of 50% of
oxidatively metabolized drugs. The predominant hepatic form is CYP3A4, but recent …

Previous results demonstrating homotropic activation of human UDP-glucuronosyltransferase
(UGT) 1A1-catalyzed estradiol-3-glucuronidation led us to investigate the effects of 16 …

BACKGROUND Surgical stabilization of rib fractures (SSRFs) continues to gain popularity
due to patient benefits. However, little has been produced regarding the economic benefits of …

… Survival curves and statistical comparisons between different groups are shown (E). The
tumor start … We thank E. Emslie for technical assistance with mouse genotyping, A. Gardner, A. …

Cytoskeletal rearrangements are central to endothelial cell physiology and are controlled by
soluble factors, matrix proteins, cell-cell interactions, and mechanical forces. We previously …

BACKGROUND Chest wall injury in older adults is a significant cause of morbidity and
mortality. Optimal nonsurgical management strategies for these patients have not been fully …

Ectopic expression of a constitutive active mutant of the GTPase Cdc42 (V12Cdc42) in vascular
endothelial cells triggers the dissolution of stress fibres and focal adhesion contacts and …

Hairy cell leukemia is an uncommon B-cell lymphoproliferative disease of unknown etiology
in which tumor cells display characteristic microfilamentous membrane projections. Another …

… Cantrell, who first described the condition in 1958. Cantrell Pentalogy is an extremely rare
… This case report presents the diagnosis of Cantrell Pentalogy in a female patient at birth and …

Tetralogy of Fallot associated with the atrioventricular canal defect has been usually reported
in association with Down syndrome. The aim of the present study was to describe the …