Reviews specific literature since 1972 covering the main new studies of the biochemistry of
cannabis metabolites, of their cellular and toxicological effects, and effects on the human …

The pharm. COkir* tIcS of ‘-tetrahydrocannabino1 (A-THC) has bonn studied in rabbits under
conditions of single or multiple administra-tion. Measurement of the drug was by a sensitive …

The in vivo metabolism of cannabidiol (CBD) was investigated in mice. Following the ip
administration of CBD to mice, livers were removed and metabolites were extracted with ethyl …

METHODS For most of the experiments mice were used, not of homogeneous origin, weighing
20-30 g. They were compressed in groups of six or eight in a small compression chamber …

Metabolites of delta 6-tetrahydrocannabinol (THC) were extracted from livers, separated
from lipids by chromatography on Sephadex LH-20, and identified by combined gas …

1. Bubble formation in the hind limb of anaesthetized guinea‐pigs, after decompression from
two different saturation exposures to air, 0.69 and 0.83 MPa gauge, has been studied using …

Glucuronide conjugates of cannabidiol (CBD), 7-hydroxy-CBD, propyl-CBD, cannabinol (CBN),
7-hydroxy-CBN, CBN-7-oic acid, propyl CBN and cannabichromene have been …

Experiments to investigate pressure-induced antagonism of the effects of general anaesthetics
in isolated peripheral nerve from the frog are described. The doses of four gaseous …

An high-resolution pulse echo ultrasonic imaging system has been developed to study
decompression-induced gas bubbles. It was considered necessary that the system be capable of …

Department ofPharmacology, University of Oxford, Oxford OX1 3QT Four groups of rabbits
were used. Each of the first group,'acute cannabis', received 50 mg/kg crude cannabis (100 mg…