User profiles for Wouter H. J. Vaes

Wouter HJ Vaes

Senior Scientist, Microtracers in early clinical development
Verified email at tno.nl
Cited by 5618

Sensing dissolved sediment porewater concentrations of persistent and bioaccumulative pollutants using disposable solid-phase microextraction fibers

P Mayer, WHJ Vaes, F Wijnker… - Environmental …, 2000 - ACS Publications
Polymer coated glass fibers were applied as disposable samplers to measure dissolved
concentrations of persistent and bioaccumulative pollutants (PBPs) in sediment porewater. The …

Measurement of the free concentration using solid-phase microextraction: Binding to protein

WHJ Vaes, E Urrestarazu Ramos… - Analytical …, 1996 - ACS Publications
A method is described to measure freely dissolved compounds, using solid-phase microextraction
(SPME) as sampling technique. Currently applied techniques, like solvent extraction, …

Absorption of hydrophobic compounds into the poly (dimethylsiloxane) coating of solid-phase microextraction fibers: High partition coefficients and fluorescence …

P Mayer, WHJ Vaes, JLM Hermens - Analytical Chemistry, 2000 - ACS Publications
The use of solid-phase microextraction with poly(dimethylsiloxane) (PDMS)-coated glass
fibers for the extraction and analysis of hydrophobic organic analytes is increasing. The …

Bioavailability and kinetics of sulforaphane in humans after consumption of cooked versus raw broccoli

…, R van den Berg, WHJ Vaes - Journal of agricultural …, 2008 - ACS Publications
The aim of this study was to determine the bioavailability and kinetics of the supposed
anticarcinogen sulforaphane, the hydrolysis product of glucoraphanin, from raw and cooked …

Solid Phase Microextraction as a Tool To Determine Membrane/Water Partition Coefficients and Bioavailable Concentrations in in Vitro Systems

WHJ Vaes, E Urrestarazu Ramos… - Chemical research in …, 1997 - ACS Publications
Solid phase microextraction (SPME) is an extraction technique that uses a polymer-coated
fiber as the extraction device. After extraction, the compound of interest can be desorbed from …

Acute toxicity of nonpolar versus polar narcosis: Is there a difference?

WHJ Vaes, EU Ramos, HJM Verhaar… - … and Chemistry: An …, 1998 - Wiley Online Library
Narcosis I and II chemicals exhibit different lethal body burdens (LBBs) and acute toxicities (median
lethal concentrations [LC50's]) in fish, when compared with their log n‐octanol‐water …

[HTML][HTML] A vegetable/fruit concentrate with high antioxidant capacity has no effect on biomarkers of antioxidant status in male smokers

…, WMR Broekmans, NHP Cnubben, WHJ Vaes… - The Journal of …, 2001 - Elsevier
The potential benefits of a high fruit and vegetable intake on the antioxidant status and on
relevant biomarkers of oxidative damage to lipids, proteins and DNA and on (functional) …

[PDF][PDF] Using solid-phase microextraction to determine partition coefficients to humic acids and bioavailable concentrations of hydrophobic chemicals

EU Ramos, SN Meijer, WHJ Vaes… - … science & technology, 1998 - lib3.dss.go.th
In the current study, the suitability of negligible depletion solid-phase microextraction (nd-SPME)
to determine free fractions of chemicals in aquatic environments was explored. The …

Predicting blood: air partition coefficients using basic physicochemical properties

…, L de Wit-Bos, T Bouwman, WHJ Vaes - Regulatory Toxicology and …, 2012 - Elsevier
Quantitative Property Property Relationships (QPPRs) for human and rat blood:air partition
coefficients (PBAs) have been derived, based on vapour pressure (Log(VP)), the octanol:…

Influence of pH and other modifying factors on the distribution behavior of 4-quinolones to solid phases and humic acids studied by “negligible-depletion” SPME …

HC Holten Lützhøft, WHJ Vaes, AP Freidig… - … science & technology, 2000 - ACS Publications
Flumequine, oxolinic acid, and sarafloxacin are 4-quinolone antimicrobials that are used in
fish farming. The objective of this investigation was to study the influence of pH on the …