[HTML][HTML] Heparan sulfate 3-O-sulfotransferase isoform 5 generates both an antithrombin-binding site and an entry receptor for herpes simplex virus, type 1
Heparan sulfate 3-O-sulfotransferase transfers sulfate to the 3-OH position of a glucosamine
residue of heparan sulfate (HS) to form 3-O-sulfated HS. The 3-O-sulfated glucosamine …
residue of heparan sulfate (HS) to form 3-O-sulfated HS. The 3-O-sulfated glucosamine …
Transport of dicationic drugs pentamidine and furamidine by human organic cation transporters
X Ming, W Ju, H Wu, RR Tidwell, JE Hall… - Drug Metabolism and …, 2009 - ASPET
The antiparasitic activity of aromatic diamidine drugs, pentamidine and furamidine, depends
on their entry into the pathogenic protozoa via membrane transporters. However, no such …
on their entry into the pathogenic protozoa via membrane transporters. However, no such …
Matrin 3 is a Ca2+/calmodulin-binding protein cleaved by caspases
CA Valencia, W Ju, R Liu - Biochemical and biophysical research …, 2007 - Elsevier
Matrin 3 is a nuclear matrix protein that has been implicated in interacting with other nuclear
proteins to anchor hyperedited RNAs to the nuclear matrix, in modulating the activity of …
proteins to anchor hyperedited RNAs to the nuclear matrix, in modulating the activity of …
Proteome-wide identification of family member-specific natural substrate repertoire of caspases
W Ju, CA Valencia, H Pang, Y Ke… - Proceedings of the …, 2007 - National Acad Sciences
Caspases are proteolytic enzymes that are essential for apoptosis. Understanding the many
discrete and interacting signaling pathways mediated by caspases requires the …
discrete and interacting signaling pathways mediated by caspases requires the …
[HTML][HTML] A chiral HPLC-MS/MS method for simultaneous quantification of warfarin enantiomers and its major hydroxylation metabolites of CYP2C9 and CYP3A4 in …
Warfarin is an oral anticoagulant that requires frequent therapeutic drug monitoring due to a
narrow therapeutic window, considerable interindividual variability in drug response, and …
narrow therapeutic window, considerable interindividual variability in drug response, and …
[HTML][HTML] A simple protein precipitation-based simultaneous quantification of lovastatin and its active metabolite lovastatin acid in human plasma by ultra-performance …
J Wujian, P Kuan-wei, Y Sihyung, S Huijing… - … of chromatography & …, 2015 - ncbi.nlm.nih.gov
Lovastatin is an anti-cholesterol lactone drug indicated for the treatment of hyperlipidemia
and to reduce the risk of coronary heart disease. It is converted to the β-hydroxy acid form (…
and to reduce the risk of coronary heart disease. It is converted to the β-hydroxy acid form (…
CYP 1 A 1 and CYP 1 B 1‐Mediated Biotransformation of the Antitrypanosomal Methamidoxime Prodrug DB 844 Forms Novel Metabolites Through Intramolecular …
W Ju, S Yang, JH Ansede, CE Stephens… - Journal of …, 2014 - Wiley Online Library
DB 844 ( CPD ‐594–12), N‐methoxy‐6‐{5‐[4‐(N‐methoxyamidino)phenyl]‐furan‐2‐yl}‐nicotinamidine,
is an oral prodrug that has shown promising efficacy in both mouse and monkey …
is an oral prodrug that has shown promising efficacy in both mouse and monkey …
Four-color DNA sequencing by synthesis using cleavable fluorescent nucleotide reversible terminators
DNA sequencing by synthesis (SBS) on a solid surface during polymerase reaction offers a
paradigm to decipher DNA sequences. We report here the construction of such a DNA …
paradigm to decipher DNA sequences. We report here the construction of such a DNA …
Generation of vascularized brain organoids to study neurovascular interactions
XY Sun, XC Ju, Y Li, PM Zeng, J Wu, YY Zhou… - Elife, 2022 - elifesciences.org
Brain organoids have been used to recapitulate the processes of brain development and
related diseases. However, the lack of vasculatures, which regulate neurogenesis and brain …
related diseases. However, the lack of vasculatures, which regulate neurogenesis and brain …
Four-color DNA sequencing with 3′-O-modified nucleotide reversible terminators and chemically cleavable fluorescent dideoxynucleotides
DNA sequencing by synthesis (SBS) on a solid surface during polymerase reaction can
decipher many sequences in parallel. We report here a DNA sequencing method that is a hybrid …
decipher many sequences in parallel. We report here a DNA sequencing method that is a hybrid …