Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease
…, X Cheng, X Cen, S Hu, X Yang, J Wang, X Liu… - Science, 2020 - science.org
… The x-ray crystal structures of SARS-CoV-2 M pro in complex with 11a or 11b, both determined
at a resolution of 1.5 angstroms, showed that the aldehyde groups of 11a and 11b are …
at a resolution of 1.5 angstroms, showed that the aldehyde groups of 11a and 11b are …
Bat algorithm: literature review and applications
XS Yang, X He - International Journal of Bio-inspired …, 2013 - inderscienceonline.com
… f(x) = 0. As the minimum or maximum of a function f(x) has to satisfy the critical condition f’(x)
= 0, therefore, this optimisation problem now becomes a problem of finding the roots of f’(x)…
= 0, therefore, this optimisation problem now becomes a problem of finding the roots of f’(x)…
[HTML][HTML] Role of angiotensin-converting enzyme 2 (ACE2) in COVID-19
W Ni, X Yang, D Yang, J Bao, R Li, Y Xiao, C Hou… - Critical Care, 2020 - Springer
An outbreak of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
that started in Wuhan, China, at the end of 2019 has become a global pandemic. …
that started in Wuhan, China, at the end of 2019 has become a global pandemic. …
Pathways for practical high-energy long-cycling lithium metal batteries
… Among the reported lithium intercalation cathode materials 1 , we select high-Ni NMC (LiNi
x M 1−x O 2 , M = Mn, Co and x ≥ 0.6) based on the consideration of its capacity (greater …
x M 1−x O 2 , M = Mn, Co and x ≥ 0.6) based on the consideration of its capacity (greater …
Single-atom catalysts: a new frontier in heterogeneous catalysis
… our recent work on Pt 1 /FeO x , have provided unambiguous evidence that SACs can have
… The development of Pt 1 /FeO x has exclusively proven that supported single atoms can be …
… The development of Pt 1 /FeO x has exclusively proven that supported single atoms can be …
Circular RNA: a new star of noncoding RNAs
Circular RNAs (circRNAs) are a novel type of RNA that, unlike linear RNAs, form a covalently
closed continuous loop and are highly represented in the eukaryotic transcriptome. Recent …
closed continuous loop and are highly represented in the eukaryotic transcriptome. Recent …
[HTML][HTML] Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase
… on ice followed by permeabilization with 0.1% Triton X-100 and 0.05% NP-40 on ice. After
pre-… . In brief, cells grown on coverslips were permeabilized with 0.05% Triton X-100 in 20 mM …
pre-… . In brief, cells grown on coverslips were permeabilized with 0.05% Triton X-100 in 20 mM …
[PDF][PDF] ALKBH5 is a mammalian RNA demethylase that impacts RNA metabolism and mouse fertility
N 6 -methyladenosine (m 6 A) is the most prevalent internal modification of messenger RNA
(mRNA) in higher eukaryotes. Here we report ALKBH5 as another mammalian demethylase …
(mRNA) in higher eukaryotes. Here we report ALKBH5 as another mammalian demethylase …
[HTML][HTML] FTO-dependent demethylation of N6-methyladenosine regulates mRNA splicing and is required for adipogenesis
The role of Fat Mass and Obesity-associated protein (FTO) and its substrate N6-methyladenosine
(m 6 A) in mRNA processing and adipogenesis remains largely unknown. We show …
(m 6 A) in mRNA processing and adipogenesis remains largely unknown. We show …
[HTML][HTML] A pneumonia outbreak associated with a new coronavirus of probable bat origin
… -004-001 to PZ), Youth innovation promotion association of CAS (2019328 to X.-LY). …
The x axis indicates the genome nucleotide position and the y axis represents the read …
The x axis indicates the genome nucleotide position and the y axis represents the read …