[HTML][HTML] Capmatinib in MET Exon 14–Mutated or MET-Amplified Non–Small-Cell Lung Cancer

…, B Sankaran, OA Balbin, X Cui… - … England Journal of …, 2020 - Mass Medical Soc
Background Among patients with non–small-cell lung cancer (NSCLC), MET exon 14
skipping mutations occur in 3 to 4% and MET amplifications occur in 1 to 6%. Capmatinib, a …

Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5-Chloro-N2-(2-isopropoxy-5 …

…, Y Kim, B Liu, T Tuntland, X Cui… - Journal of medicinal …, 2013 - ACS Publications
The synthesis, preclinical profile, and in vivo efficacy in rat xenograft models of the novel and
selective anaplastic lymphoma kinase inhibitor 15b (LDK378) are described. In this initial …

Discovery of (1R,5S)-N-[3-Amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3 …

…, A Prongay, V Madison, L Broske, X Cui… - Journal of medicinal …, 2006 - ACS Publications
Hepatitis C virus (HCV) infection is the major cause of chronic liver disease, leading to
cirrhosis and hepatocellular carcinoma, which affects more than 170 million people worldwide. …

[PDF][PDF] A literature review on organization culture and corporate performance

X Cui, J Hu - International Journal of Business Administration, 2012 - academia.edu
From 1980s, there are more and more studies about organization culture. And in Chinese
studies and practices, we pay much attention to the culture due to the direct relationship …

Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C

…, KS Beyer, C Bomio-Confaglia, H Burks, X Chen, X Cui… - Cancer Discovery, 2022 - AACR
JDQ443 is a structurally novel covalent KRAS G12C inhibitor with a unique binding mode
that demonstrates potent and selective antitumor activity in cell lines and in vivo models. In …

Perceptions of place, modernity and the impacts of tourism–Differences among rural and urban residents of Ankang, China: A likelihood ratio analysis

X Cui, C Ryan - Tourism Management, 2011 - Elsevier
This paper reports results from a survey of urban and rural residents’ of the perceived
impacts of change induced by tourism in Ankang, China. The paper will initially indicate the …

[HTML][HTML] Distribution of Haemaphysalis longicornis and associated pathogens: analysis of pooled data from a China field survey and global published data

L Zhao, J Li, X Cui, N Jia, J Wei, L Xia… - The Lancet Planetary …, 2020 - thelancet.com
Background Haemaphysalis longicornis, a vector of various pathogens with medical and
veterinary importance, is native to eastern Asia, and recently reached the USA as an emerging …

Development of a novel in vitro model to predict hepatic clearance using fresh, cryopreserved, and sandwich-cultured hepatocytes

YY Lau, E Sapidou, X Cui, RE White… - Drug metabolism and …, 2002 - ASPET
Sixty-four compounds with diverse structures were used in evaluation of intrinsic clearance
by various hepatocyte preparations from rats, dogs, monkeys, and humans. Intrinsic …

Targeted delivery of quercetin by nanoparticles based on chitosan sensitizing paclitaxel-resistant lung cancer cells to paclitaxel

Y Wang, H Yu, S Wang, C Gai, X Cui, Z Xu, W Li… - Materials Science and …, 2021 - Elsevier
Chemotherapy plays crucial roles in the clinical treatment of non-small cell lung cancer (NSCLC).
Nevertheless, acquired chemoresistance is a common and critical problem that limits …

Rolling reduction-dependent deformation mechanisms and tensile properties in a β titanium alloy

…, R Chen, F Liu, J Zhang, F Yang, X Zhao, X Cui… - Journal of Materials …, 2022 - Elsevier
This work investigated the dependence of deformation mechanisms and mechanical properties
on cold rolling reductions of the metastable TB8 titanium alloy. Results shown that the …