Long-term neurologic outcome of hemilaminectomy and disk fenestration for treatment of dogs with thoracolumbar intervertebral disk herniation: 831 cases (2000 …
…, S Kanazono, M Shibata, Y Yoshigae - Journal of the …, 2012 - Am Vet Med Assoc
Objective —To determine the proportion of dogs with thoracolumbar intervertebral disk
herniation (IVDH) that successfully recovered following hemilaminectomy and fenestration, the …
herniation (IVDH) that successfully recovered following hemilaminectomy and fenestration, the …
Edoxaban transport via P-glycoprotein is a key factor for the drug's disposition
T Mikkaichi, Y Yoshigae, H Masumoto, T Imaoka… - Drug Metabolism and …, 2014 - ASPET
Edoxaban (the free base of DU-176b), an oral direct factor Xa inhibitor, is mainly excreted
unchanged into urine and feces. Because active membrane transport processes such as …
unchanged into urine and feces. Because active membrane transport processes such as …
OATP1B1, OATP1B3, and mrp2 are involved in hepatobiliary transport of olmesartan, a novel angiotensin II blocker
…, D Nakai, K Kawai, Y Yoshigae… - Drug Metabolism and …, 2006 - ASPET
Hepatic uptake and biliary excretion of olmesartan, a new angiotensin II blocker, were
investigated in vitro using human hepatocytes, cells expressing uptake transporters and …
investigated in vitro using human hepatocytes, cells expressing uptake transporters and …
Catheter ablation of long-standing persistent atrial fibrillation: 5-year outcomes of the Hamburg Sequential Ablation Strategy
…, P Wohlmuth, A Metzner, S Mathew, Y Yoshiga… - Journal of the American …, 2012 - jacc.org
Objectives : This study describes the 5-year efficacy of catheter ablation for long-standing
persistent atrial fibrillation (LS-AF). Background : Long-term outcome data after catheter …
persistent atrial fibrillation (LS-AF). Background : Long-term outcome data after catheter …
Vertebral stabilization using positively threaded profile pins and polymethylmethacrylate, with or without laminectomy, for spinal canal stenosis and vertebral instability …
T Aikawa, S Kanazono, Y Yoshigae… - Veterinary …, 2007 - Wiley Online Library
Objective— To describe diagnostic findings, surgical technique, and outcome in dogs with
thoracic spinal canal stenosis and vertebral instability secondary to congenital vertebral …
thoracic spinal canal stenosis and vertebral instability secondary to congenital vertebral …
[HTML][HTML] Human carboxymethylenebutenolidase as a bioactivating hydrolase of olmesartan medoxomil in liver and intestine
…, M Kato, C Noji-Sakikawa, M Saito, Y Yoshigae… - Journal of biological …, 2010 - ASBMB
Olmesartan medoxomil (OM) is a prodrug type angiotensin II type 1 receptor antagonist
widely prescribed as an antihypertensive agent. Herein, we describe the identification and …
widely prescribed as an antihypertensive agent. Herein, we describe the identification and …
Comparison of expression of connexin in right atrial myocardium in patients with chronic atrial fibrillation versus those in sinus rhythm
…, T Matsumoto, J Yamada, A Shimizu, Y Yoshiga… - The American journal of …, 2003 - Elsevier
An abnormal distribution of the gap junction occurs in chronic atrial fibrillation (AF). There
are conflicting data regarding changes in connexins (Cxs) in experimental models of AF. We …
are conflicting data regarding changes in connexins (Cxs) in experimental models of AF. We …
Adjuvant activity mediated by iNKT cells
…, S Motohashi, K Shimizu, T Nakayama, Y Yoshiga… - Seminars in …, 2010 - Elsevier
Invariant natural killer T (iNKT) cells have adjuvant activity due to their ability to produce
large amounts of IFN-γ, which activates other cells in innate and acquired systems, and …
large amounts of IFN-γ, which activates other cells in innate and acquired systems, and …
Invariant NKT cells produce IL-17 through IL-23-dependent and-independent pathways with potential modulation of Th17 response in collagen-induced arthritis …
Y Yoshiga, D Goto, S Segawa… - International …, 2008 - spandidos-publications.com
Invariant natural killer T (iNKT) cells play a protective role in the development of certain
autoimmune diseases. However, their precise role in the pathogenesis of autoimmune arthritis …
autoimmune diseases. However, their precise role in the pathogenesis of autoimmune arthritis …
The inactivation of human CYP2E1 by phenethyl isothiocyanate, a naturally occurring chemopreventive agent, and its oxidative bioactivation
Y Yoshigae, C Sridar, UM Kent, PF Hollenberg - Drug Metabolism and …, 2013 - ASPET
… The identities of the b and y ions for the modified peptide … the y 4 to the y 7 ions with an
increase in the mass of the y 8 … that expected for y 8 and the observed y 8 ion indicated that the …
increase in the mass of the y 8 … that expected for y 8 and the observed y 8 ion indicated that the …