[PDF][PDF] IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

J Schmitz, A Owyang, E Oldham, Y Song, E Murphy… - Immunity, 2005 - cell.com
Cytokines of the interleukin-1 (IL-1) family, such as IL-1α/β and IL-18, have important
functions in host defense, immune regulation, and inflammation. Insight into their biological …

An activating immunoreceptor complex formed by NKG2D and DAP10

J Wu, Y Song, ABH Bakker, S Bauer, T Spies, LL Lanier… - Science, 1999 - science.org
Many immune receptors are composed of separate ligand-binding and signal-transducing
subunits. In natural killer (NK) and T cells, DAP10 was identified as a cell surface adaptor …

Characterization of the CD200 receptor family in mice and humans and their interactions with CD200

…, G Brooke, MJ Puklavec, M Bigler, Y Song… - The Journal of …, 2003 - journals.aai.org
CD200 (OX2) is a broadly distributed cell surface glycoprotein that interacts with a structurally
related receptor (CD200R) expressed on rodent myeloid cells and is involved in regulation …

The CD200 receptor is a novel and potent regulator of murine and human mast cell function

…, CA Murphy, BL Joyce, ME Bigler, YS Song… - the Journal of …, 2005 - journals.aai.org
CD200R is a member of the Ig supergene family that is primarily expressed on myeloid cells.
Recent in vivo studies have suggested that CD200R is an inhibitory receptor capable of …

Generic automated method for liquid chromatography–multiple reaction monitoring mass spectrometry based monoclonal antibody quantitation for preclinical …

Q Zhang, DS Spellman, Y Song, B Choi… - Analytical …, 2014 - ACS Publications
Quantitation of therapeutic monoclonal antibodies (mAb) using liquid chromatography–tandem
mass spectrometry (LC–MS/MS) for pharmacokinetic (PK) studies is becoming an …

Effects of PEGylation and immune complex formation on the pharmacokinetics and biodistribution of recombinant interleukin 10 in mice

…, SC Hsieh, N Shinsky-Bjorde, H Ma, Y Song… - Drug Metabolism and …, 2012 - ASPET
Interleukin 10 (IL-10) is a potent cytokine homodimer with multiple immunoregulatory functions.
Here, we have characterized the effects of PEGylation and formation of human IL-10 (hIL-…

Tumor necrosis factor‐α and basic fibroblast growth factor decrease glial fibrillary acidic protein and its encoding mRNA in astrocyte cultures and glioblastoma cells

…, XC Jia, ACH Yu, A Majewska, Y Song… - Journal of …, 1995 - Wiley Online Library
Tumor necrosis factor‐α is a pluripotent cytokine that is reportedly mitogenic to astrocytes.
We examined expression of the astrocyte intermediate filament component glial fibrillary …

Pharmacokinetic Properties of Humanized IgG1 and IgG4 Antibodies in Preclinical Species: Translational Evaluation

…, SC Hseih, L Fayadat-Dilman, D Zhang, Y Song… - The AAPS Journal, 2019 - Springer
Assessment of the factors that regulate antibody exposure–response relationships in the
relevant animal models is critical for the design of successful translational strategies from …

Expression of interleukin-11 and its encoding mRNA by glioblastoma cells

…, L Bitting, A Majewska, K Schmidt, Y Song… - Neuroscience …, 1995 - Elsevier
Interleukin-11 (IL-11) is a pleiotropic cytokine with important effects on hematopoietic and
other cells. IL-11 was originally described as a product of stromal cell lines and fibroblasts. …

Circulating microRNAs: promising biomarkers involved in several cancers and other diseases

Y Zhao, Y Song, L Yao, G Song, C Teng - DNA and cell biology, 2017 - liebertpub.com
Recently, many studies indicated that microRNAs (miRNAs) stably existed in various body
fluids, including serum, plasma, saliva, and urine. Such miRNAs that exist in mammalian body …