1,25-Dihydroxyvitamin D 3 (1,25(OH) 2 D 3 ) is known to induce the expression of
cytochrome P450 3A4 (CYP3A4) in human colon carcinoma Caco-2 cells. Recently, it was …

Expression of cytochrome P450 3A4 (CYP3A4) is induced by 1,25-dihydroxyvitaminD 3 (1,25(OH)
2 D 3 ) in Caco-2 cells. However, since a typical vitamin D responsive element has not …

Cytochrome P450 3A4 and 3A7 (CYP3A4 and CYP3A7, respectively) are predominant forms
in the human adult and fetal liver, respectively. 1,25-Dihydroxyvitamin D 3 (1,25(OH) 2 D 3 …

The purpose of this study was to evaluate the effects of a poly(lactic-co-glycolic acid) (PLGA)
membrane containing fluvastatin on bone regeneration at bone defects in rat calvaria and …

For the identification of susceptibility loci for primary biliary cirrhosis (PBC), a genome-wide
association study (GWAS) was performed in 963 Japanese individuals (487 PBC cases and …

Aims: Anti‐gp210 and anti‐centromere antibodies are different risk factors for the progression
of primary biliary cirrhosis (PBC). However, the association of human leukocyte antigen (…

Identification of the primary allele(s) in HLA class II associated diseases remains challenging
because of a tight linkage between alleles of HLA-DR and -DQ loci. In the present study, …

A previous genome-wide association study (GWAS) performed in 963 Japanese individuals
(487 primary biliary cholangitis [PBC] cases and 476 healthy controls) identified TNFSF15 (…

Background/Aims Recent studies demonstrated an association of STAT4 polymorphisms
with autoimmune diseases including systemic lupus erythematosus and rheumatoid arthritis, …

High intake of red meat has been associated with increased risk of colorectal cancer in
Western countries. There has been much interest in the role of n‐3 polyunsaturated fatty acids (…