The mathematical representation of smoking history is an important tool in analysis of
epidemiological and clinical data. Hoffmann and colleagues recently proposed a single aggregate …

Background— FTO is the first gene established as contributing to common forms of obesity.
The gene is highly expressed in the hypothalamus and is thought to mediate this effect …

Objective To investigate the association between intra-abdominal adiposity and individual
components of the metabolic syndrome (MS) in adolescent males and females. Design Cross-…

Background: Patients with HIV exposed to the antiretroviral drug abacavir may have an
increased risk of cardiovascular disease (CVD). There is concern that this association arises …

… Yongling Xiao holds a doctoral research scholarship from the Fonds de Recherche sur la
Nature et les Technologies du Québec (FQRNT). Michal Abrahamowicz is a James McGill …

Objectives To investigate during adolescence (1) sex differences in blood pressure (BP) and
hemodynamic factors at rest and during physical and mental challenges and (2) whether …

Marginal structural Cox Models (Cox MSMs) have been used to estimate the causal effect of
a time-varying treatment on the hazard when there exist time-dependent confounders, …

Objective Care in rheumatoid arthritis (RA) is optimized by involvement of rheumatologists.
We wished to determine whether patients suspected of having new‐onset RA in Québec …

Background Education is inversely associated with cardiovascular disease incidence in
developed countries. Blood pressure may be an explanatory biological mechanism. However …

In the present study, we characterized in vitro biosynthesis and disposition of bile acids (BAs)
as well as hepatic transporter expression followed by ABCB11 (BSEP) gene knockout in …