Downregulation of microRNAs‐143 and‐145 in B‐cell malignancies

Y Akao, Y Nakagawa, Y Kitade, T Kinoshita… - Cancer …, 2007 - Wiley Online Library
Recently, it has been found that inappropriate expression of microRNAs (miRNAs) is strongly
associated with carcinogenesis. In this study, we demonstrated that the expression of …

[HTML][HTML] Putative ACP phosphodiesterase gene (acpD) encodes an azoreductase

M Nakanishi, C Yatome, N Ishida, Y Kitade - Journal of Biological Chemistry, 2001 - ASBMB
An FMN-dependent NADH-azoreductase ofEscherichia coli was purified and analyzed for
identification of the gene responsible for azo reduction by microorganisms. The N-terminal …

[HTML][HTML] Epidemiological, molecular characterization and antibiotic resistance of Salmonella enterica serovars isolated from chicken farms in Egypt

…, M El-Abasy, F El-Khayat, T Gillespie, Y Kitade… - Gut Pathogens, 2017 - Springer
Background Salmonella is one of major causes of foodborne outbreaks globally. This study
was conducted to estimate the prevalence, typing and antibiotic susceptibilities of …

MicroRNA-143 functions as a tumor suppressor in human bladder cancer T24 cells

…, T Mori, Y Hoshino, K Maruo, N Yamada, Y Kitade… - Cancer letters, 2011 - Elsevier
MicroRNA (miR)-143 and -145 were down-regulated in human bladder cancer T24 cells.
The enforced expression of miR-143 induced growth-suppression in T24 cells through down-…

Inhibition of the DNA-binding activity of NF-κB by gold compounds in vitro

JP Yang, JP Merin, T Nakano, T Kato, Y Kitade… - FEBS letters, 1995 - Elsevier
Nuclear factor κB (NF-κB) is a transcription factor that is critical for the inducible expression
of multiple cellular and viral genes. DNA binding activity is essential for its function. Here, we …

MicroRNAs and their therapeutic potential for human diseases: microRNAs, miR-143 and-145, function as anti-oncomirs and the application of chemically modified …

Y Kitade, Y Akao - Journal of pharmacological sciences, 2010 - Elsevier
We examined the expression levels of microRNAs (miRNAs; miRs) in colorectal tumors (63
cancer specimens and 65 adenoma specimens) compared to adjacent non-tumorous tissues…

[HTML][HTML] Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum

…, N Tanaka, Y Kusakabe, M Nakanishi, Y Kitade… - Scientific Reports, 2011 - nature.com
The human malaria parasite Plasmodium falciparum is responsible for the deaths of more
than a million people each year. Fosmidomycin has been proven to be efficient in the …

Structural basis for recognition of 2′, 5′‐linked oligoadenylates by human ribonuclease L

…, M Nakanishi, Y Kusakabe, Y Goto, Y Kitade… - The EMBO …, 2004 - embopress.org
An interferon‐induced endoribonuclease, ribonuclease L (RNase L), is implicated in both the
molecular mechanism of action of interferon and the fundamental control of RNA stability in …

Kinetic studies of AKR1B10, human aldose reductase-like protein: endogenous substrates and inhibition by steroids

…, H Mamiya, C Ohta, M Soda, Y Kitade… - Archives of biochemistry …, 2009 - Elsevier
A human member of the aldo–keto reductase (AKR) superfamily, AKR1B10, was identified
as a biomarker of lung cancer, exhibiting high sequence identity with human aldose …

Ligand‐Free and Heterogeneous Palladium on Carbon‐Catalyzed Hetero‐Suzuki–Miyaura Cross‐Coupling

…, Y Monguchi, T Maegawa, Y Kitade… - Advanced Synthesis …, 2010 - Wiley Online Library
A ligand‐free and heterogeneous palladium on carbon (Pd/C)‐catalyzed hetero‐Suzuki–Miyaura
coupling reaction has been developed. The protocol enables the construction of both …