Inhibitory effects of fruit juices on CYP3A activity
H Kim, YJ Yoon, JH Shon, IJ Cha, JG Shin… - Drug metabolism and …, 2006 - ASPET
There have been very limited reports on the effects of commercial fruit juices on human
CYP3A activity. Therefore, the inhibitory effects of readily available commercial fruit juices on …
CYP3A activity. Therefore, the inhibitory effects of readily available commercial fruit juices on …
Characterization of ebastine, hydroxyebastine, and carebastine metabolism by human liver microsomes and expressed cytochrome P450 enzymes: major roles for …
KH Liu, MG Kim, DJ Lee, YJ Yoon, MJ Kim… - Drug metabolism and …, 2006 - ASPET
Ebastine undergoes extensive metabolism to form desalkylebastine and hydroxyebastine.
Hydroxyebastine is subsequently metabolized to carebastine. Although CYP3A4 and CYP2J2 …
Hydroxyebastine is subsequently metabolized to carebastine. Although CYP3A4 and CYP2J2 …
Characterization of benidipine and its enantiomers' metabolism by human liver cytochrome P450 enzymes
YJ Yoon, KB Kim, H Kim, KA Seo, HS Kim, IJ Cha… - Drug metabolism and …, 2007 - ASPET
Benidipine is a dihydropyridine calcium antagonist that has been used clinically as an
antihypertensive and antianginal agent. It is used clinically as a racemate, containing the (-)-α and …
antihypertensive and antianginal agent. It is used clinically as a racemate, containing the (-)-α and …
The effect of CYP2C19 genotype on the time course of platelet aggregation inhibition after clopidogrel administration
…, DY Cho, BM Park, SK Bae, YJ Yoon… - The Journal of …, 2014 - Wiley Online Library
We evaluated the effect of CYP2C19 genotype over time on the antiplatelet response of
clopidogrel in healthy subjects. Seventy subjects enrolled for a pharmacodynamic study and 22 …
clopidogrel in healthy subjects. Seventy subjects enrolled for a pharmacodynamic study and 22 …
Potential of hydroxyebastine and terfenadine alcohol to inhibit the human cytochrome P450 2J2 isoform
YJ Yoon, KH Liu - Journal of the Korean Society for Applied Biological …, 2011 - Springer
Although selective inhibitors of cytochrome P450 enzymes can be used to determine relative
contributions of the enzymes to xenobiotic metabolism, characterization of CYP2J2 in drug …
contributions of the enzymes to xenobiotic metabolism, characterization of CYP2J2 in drug …
Characterization of the cytochrome P450 enzymes involved in the metabolism of a new cardioprotective agent KR-33028
H Kim, YJ Yoon, H Kim, S Kang, HG Cheon, SE Yoo… - Toxicology letters, 2006 - Elsevier
KR-33028 (N-[4-cyano-benzo[b]thiophene-2-carbonyl]guanidine) is a new cardioprotective
agent for preventing ischemia-reperfusion injury. This study was performed to characterize …
agent for preventing ischemia-reperfusion injury. This study was performed to characterize …
In vitro metabolism of a new cardioprotective agent, KR‐32570, in human liver microsomes
H Kim, S Kang, H Kim, YJ Yoon, EY Cha… - … in mass spectrometry, 2006 - Wiley Online Library
KR‐32570 (5‐(2‐methoxy‐5‐chlorophenyl)furan‐2‐ylcarbonyl)guanidine) is a new reversible
Na + /H + exchanger inhibitor for preventing ischemia‐reperfusion injury. This study was …
Na + /H + exchanger inhibitor for preventing ischemia‐reperfusion injury. This study was …
In vitro metabolism of a new cardioprotective agent, KR-33028 in the human liver microsomes and cryopreserved human hepatocytes
H Kim, YJ Yoon, H Kim, EY Cha, HS Lee… - Archives of pharmacal …, 2005 - Springer
KR-33028 (N-[4-cyano-benzo[b]thiophene-2-carbonyl]guanidine) is a new cardioprotective
agent for preventing ischemia-reperfusion injury. This study was performed to identify the …
agent for preventing ischemia-reperfusion injury. This study was performed to identify the …
Benidipine is Mainly Metabolized by CYP3A in Vitro, but, Benidipine Disposition is not Influenced by CYP3A5 Genetic Polymorphism
YJ Yoon - 대한임상약리학회: 학술대회논문집, 2006 - koreascience.kr
… Yoon, Yune-Jung (Inje University College of Medicine) …
[CITATION][C] DRUG METABOLISM AND DISPOSITION
A PIKULEVA, H KIM, YJ YOON, JIH SHON - ASPET