Presence and activity of cytochrome P450 isoforms in minipig liver microsomes: comparison with human liver samples
…, E Anzenbacherová, I Gut, K Hruby, Z Svoboda… - Drug Metabolism and …, 1998 - ASPET
Cytochrome P450 (CYP) of the 3A family (CYP3A) has been detected in minipig liver microsomes
by immunochemical screening (Western blotting), revealing bands that co-migrate with …
by immunochemical screening (Western blotting), revealing bands that co-migrate with …
[PDF][PDF] Caco-2 cells, biopharmaceutics classification system (BCS) and biowaiver
…, V Stetinova, Z Svoboda… - Acta Medica (Hradec …, 2011 - actamedica.lfhk.cuni.cz
Almost all orally administered drugs are absorbed across the intestinal mucosa. The Caco-2
monolayers are used as an in vitro model to predict drug absorption in humans and to …
monolayers are used as an in vitro model to predict drug absorption in humans and to …
High-performance liquid chromatographic method with UV photodiode-array, fluorescence and mass spectrometric detection for simultaneous determination of …
J Maláková, M Nobilis, Z Svoboda, M Lísa… - … of Chromatography B, 2007 - Elsevier
Galantamine, an alkaloid isolated from the bulbs and flowers of Caucasian snowdrop (Galanthus
woronowii, Amaryllidaceae) and related species, is employed in human medicine for …
woronowii, Amaryllidaceae) and related species, is employed in human medicine for …
How was Neolithic pottery fired? An exploration of the effects of firing dynamics on ceramic products
The presented study is focused on the development of a new methodology for estimating
the heating rate during firing as one of the principal characteristics of the firing process. We …
the heating rate during firing as one of the principal characteristics of the firing process. We …
[PDF][PDF] Caco-2 cell monolayer integrity and effect of probiotic Escherichia coli Nissle 1917 components
…, L Smetanova, J Kvetina, Z Svoboda… - Neuroendocrinology …, 2010 - nel.altamira.sk
OBJECTIVES: Different probiotic strains used in clinical trials have shown prophylactic
properties in different inflammatory diseases of the gastrointestinal tract. This study was aimed to …
properties in different inflammatory diseases of the gastrointestinal tract. This study was aimed to …
Numerical simulation of heat transfer through hollow bricks in the vertical direction
Z Svoboda, M Kubr - Journal of Building Physics, 2011 - journals.sagepub.com
This article focuses on the numerical modeling of the heat transfer in vertical cavities with
small cross-sectional areas in hollow bricks heated from below by means of the computational …
small cross-sectional areas in hollow bricks heated from below by means of the computational …
High-performance liquid chromatographic determination of ursodeoxycholic acid after solid phase extraction of blood serum and detection-oriented derivatization
…, J Kuneš, J Kopecký, J Květina, Z Svoboda… - … of pharmaceutical and …, 2001 - Elsevier
Ursodeoxycholic acid (3α,7β-dihydroxy-5β-cholanoic acid, UDCA) is a therapeutically
applicable bile acid widely used for the dissolution of cholesterol-rich gallstones and in the …
applicable bile acid widely used for the dissolution of cholesterol-rich gallstones and in the …
[PDF][PDF] Caco-2 cells and Biopharmaceutics Classification System (BCS) for prediction of transepithelial transport of xenobiotics (model drug: Caffeine)
…, D Kholova, J Kvetina, J Smetana, Z Svoboda - Neuroendocrinology …, 2009 - nel.edu
OBJECTIVES: The Caco-2 cell monolayer model is widely used as a standard screening
tool for studying the mechanisms of cellular drug transport. Caffeine was chosen as a model …
tool for studying the mechanisms of cellular drug transport. Caffeine was chosen as a model …
[HTML][HTML] Wireless video capsule enteroscopy in preclinical studies: methodical design of its applicability in experimental pigs
…, M Kuneš, S Špelda, V Tyčová, Z Svoboda… - Digestive diseases and …, 2010 - Springer
The aim of this project was to develop a methodology to introduce wireless video capsule
endoscopy in preclinical research. Five mature female pigs (Sus scrofa domestica) were …
endoscopy in preclinical research. Five mature female pigs (Sus scrofa domestica) were …
Transient radon diffusion through radon-proof membranes: a new technique for more precise determination of the radon diffusion coefficient
M Jiranek, Z Svoboda - Building and Environment, 2009 - Elsevier
The following paper is focused on the numerical modelling of the transient radon diffusion
through radon-proof membranes during the measurement of their radon diffusion coefficient. …
through radon-proof membranes during the measurement of their radon diffusion coefficient. …