Phototherapy for neonatal jaundice
MJ Maisels, AF McDonagh - New England Journal of Medicine, 2008 - Mass Medical Soc
A newborn male infant is brought to the pediatrician's office with pronounced jaundice and a
total serum bilirubin level of 19.5 mg per deciliter. Phototherapy is considered. In term and …
total serum bilirubin level of 19.5 mg per deciliter. Phototherapy is considered. In term and …
Like a shrivelled blood orange'—bilirubin, jaundice, and phototherapy
AF McDonagh, DA Lightner - Pediatrics, 1985 - publications.aap.org
The biochemistry of bilirubin is reviewed with particular reference to newborn infants. The
formation, properties, and metabolism of bilirubin are summarized and the importance of …
formation, properties, and metabolism of bilirubin are summarized and the importance of …
Is bilirubin good for you?
AF McDonagh - Clinics in perinatology, 1990 - Elsevier
Neonatal Jaundice Bilirubin is generally considered to be a diagnostically useful, sometimes
toxic, metabolic waste product—and nothing more. Many studies, however, summarized in …
toxic, metabolic waste product—and nothing more. Many studies, however, summarized in …
Bilirubin is an antioxidant of possible physiological importance
R Stocker, Y Yamamoto, AF McDonagh, AN Glazer… - Science, 1987 - science.org
Bilirubin, the end product of heme catabolism in mammals, is generally regarded as a
potentially cytotoxic, lipid-soluble waste product that needs to be excreted. However, it is shown …
potentially cytotoxic, lipid-soluble waste product that needs to be excreted. However, it is shown …
Photodynamic therapy of malignant tumours
I Diamond, AF Mcdonagh, CB Wilson, SG Granelli… - The Lancet, 1972 - Elsevier
Porphyrins are powerful photodynamic agents which sensitise cells so that they are damaged
when exposed to light. Malignant tumours take up and retain hæmatoporphyrin to a …
when exposed to light. Malignant tumours take up and retain hæmatoporphyrin to a …
[HTML][HTML] Crystallographic analysis of human serum albumin complexed with 4Z, 15E-bilirubin-IXα
PA Zunszain, J Ghuman, AF McDonagh… - Journal of molecular …, 2008 - Elsevier
Bilirubin, an insoluble yellow-orange pigment derived from heme catabolism, accumulates
to toxic levels in individuals with impaired or immature liver function. The resulting jaundice …
to toxic levels in individuals with impaired or immature liver function. The resulting jaundice …
[31] Antioxidant activities of bile pigments: Biliverdin and bilirubin
… To remove these impurities, bilirubin is purified according to the method described by
McDonagh and Assisi. 19 A mixture of 400 mg of bilirubin IXo~ (Sigma, from bovine gallstones) …
McDonagh and Assisi. 19 A mixture of 400 mg of bilirubin IXo~ (Sigma, from bovine gallstones) …
Molecular mechanisms of phototherapy for neonatal jaundice
DA Lightner, AF McDonagh - Accounts of Chemical Research, 1984 - ACS Publications
… Tony McDonagh was born in England in 1938, carried out his undergraduate education at
the Royal … McDonagh's scientific Interests Include tetrapyrrole chemistry, photobiology and …
the Royal … McDonagh's scientific Interests Include tetrapyrrole chemistry, photobiology and …
Role of hyperbilirubinemia in the impairment of osteoblast proliferation associated with cholestatic jaundice.
…, R Okazaki, S Bonde, AF McDonagh… - The Journal of …, 1995 - Am Soc Clin Investig
Because the osteoporosis occurring in chronic cholestatic liver disease (CCLD) is associated
with decreased bone formation and is reversible by liver transplantation, substances …
with decreased bone formation and is reversible by liver transplantation, substances …
Hyperbilirubinemia results in reduced oxidative injury in neonatal Gunn rats exposed to hyperoxia
PA Dennery, AF McDonagh, DR Spitz… - Free Radical Biology …, 1995 - Elsevier
Bilirubin is a potent antioxidant in vitro. To determine whether bilirubin also is an antioxidant
in vivo, we studied markers of oxidative injury in the Gunn rat model exposed to hyperoxia. …
in vivo, we studied markers of oxidative injury in the Gunn rat model exposed to hyperoxia. …