… b, Proportions of primary tumour cells positive for Ki-67 after the indicated siRNA treatments
(n = 3). c, RT–qPCR of Myc (left) and Pvt1 (right) transcript levels (n = 3), and d, western blot …

… (B–E) NK92 cells that express the indicated CARs were co-cultured with (B) mesoneg target
cells of K562, (C) mesohigh target cells of K562meso, (D) mesolow target cells of MA148 …

… drugs have been widely used for many kinds of cancers, including imatinib for BCR-ABL
fusion in chronic myelogenous leukemia and some kinds of acute leukemia, vemurafenib for B-…

BACKGROUND. T cells expressing antigen-specific chimeric antigen receptors (CARs) improve
outcomes for CD19-expressing B cell malignancies. We evaluated a human application …

… = (b +c)/(a + b + c), where a is the integrated intensity of the undigested PCR band and b
and c are the integrated intensities of each digested product band, as previously described. …

In vivo functional investigation of oncogenes using somatic gene transfer has been successfully
exploited to validate their role in tumorigenesis. For tumour suppressor genes this has …

… (B) ATG13 is important for colocalization of ULK1 and ATG14 puncta. mCherry-ULK1 was
transiently expressed in WT ATG13 or ATG13 KO HCT116 cells. Endogenous ATG14 puncta …

… (b) Histogram displaying the number of osteosarcomas per mouse.*P = 0.0159, Student's t
test. (c) Representative SKY results from analysis of osteosarcoma tumor cells that developed …

… B eGFP expression from 2 NK cell donors 7 and 21 days after electroporation … Hargreaves
BKV, Roberts SE, Derfalvi B, Boudreau JE. Highly efficient serum-free manipulation of miRNA …

… (b) Survival curve depicting the percentage of mice with grade 3 PNST–free survival at
time of necropsy in Trp53 R270H ; Cnp-EGFR control mice compared to mice undergoing …