… muscle function and mass are presently underway (LA Frassetto, personal communication).
… Frassetto LA, Morris RC Jr & Sebastian A (2007) Dietary sodium chloride intake …

Normal adult humans eating Western diets have chronic, low-grade metabolic acidosis, the
severity of which is determined in part by the net rate of endogenous noncarbonic acid …

Background: The contemporary American diet figures centrally in the pathogenesis of numerous
chronic diseases—‘diseases of civilization’. We investigated in humans whether a diet …

Background: Natural selection has had < 1% of hominid evolutionary time to eliminate the
inevitable maladaptations consequent to the profound transformation of the human diet …

In 64 apparently healthy adult humans (ages 17-74 yr) ingesting controlled diets, we investigated
the separate and combined effects of age, glomerular filtration rate (GFR, index of age-…

Improvements in human immunodeficiency virus (HIV)-associated mortality make it difficult
to deny transplantation based upon futility. Outcomes in the current management era are …

Background. Hip fracture, a major health problem in elderly persons, varies in incidence
among the populations of different countries and is directly related to animal protein intake, a …

An organism best fits the environment described by its genes, an environment that prevailed
during the time period (millions of years) when evolution naturally selected the genes of its …

Background. Human immunodeficiency virus (HIV)-infected patients have historically been
excluded from consideration for transplantation out of concern for the effects of …

Solid organ transplantation in human immunodeficiency virus (HIV)-infected individuals
requiring concomitant use of immunosuppressants (IS) (eg cyclosporine [CsA], sirolimus [SrL], …