Background Platelet surface P-selectin is considered the “gold standard” marker of platelet
activation. Degranulated, P-selectin–positive platelets, however, aggregate with leukocytes in …

OBJECTIVES We investigated whether elevated levels of circulating monocyte-platelet
aggregates (MPA) can be used to identify patients with acute myocardial infarction (AMI). …

Cultured human hepatocytes are a valuable in vitro system for evaluating new molecular
entities as inducers of cytochrome P450 (P450) enzymes. The present study summarizes data …

… Typically two monoclonal antibodies are used, each labeled with a different fluorophore.
A wide variety of fluorophores are available for antibody conjugation (eg, phycoerythrin, …

Dominant optic atrophy (DOA) 1 , 2 and axonal peripheral neuropathy (Charcot-Marie-Tooth
type 2, or CMT2) 3 are hereditary neurodegenerative disorders most commonly caused by …

Background Oliver–McFarlane syndrome is characterised by trichomegaly, congenital
hypopituitarism and retinal degeneration with choroidal atrophy. Laurence–Moon syndrome …

Objectives : The purpose of this study was to examine the effects of glycoprotein (GP) IIb/IIIa
antagonists (abciximab, eptifibatide, and tirofiban) and other inhibitors on translocation of …

… This site, however was not required in LBRM cells, since we deleted the segment from -169
to -101 and retained the IL-I effect (Table lA). TPA and IL-I have similar actions (1) and we …

The development of the vertebrate visual system involves complex morphogenetic
interactions of cells derived from multiple embryonic lineages. Disruptions in this process are …

… The probe was 32 P-labeled using Prime-It RmT random primer labeling kit (Stratagene,
La Jolla, CA). The membrane was then exposed to a Storm 860 PhosporImager (Molecular …