[HTML][HTML] Bioengineered kidney tubules efficiently excrete uremic toxins
…, JG Peters, UM Kreuser, PH Van Den Broek… - Scientific reports, 2016 - nature.com
The development of a biotechnological platform for the removal of waste products (eg uremic
toxins), often bound to proteins in plasma, is a prerequisite to improve current treatment …
toxins), often bound to proteins in plasma, is a prerequisite to improve current treatment …
[HTML][HTML] The influence of dietary protein intake on mammalian tryptophan and phenolic metabolites
…, HAM Mutsaers, K Windey, PH Van Den Broek… - PLoS …, 2015 - journals.plos.org
… van den Broek, … van den Broek, … Pedrini MT, Levey AS, Lau J, Chalmers TC, Wang PH.
The effect of dietary protein restriction on the progression of diabetic and nondiabetic renal …
The effect of dietary protein restriction on the progression of diabetic and nondiabetic renal …
Effects of hypothermia on pharmacokinetics and pharmacodynamics: a systematic review of preclinical and clinical studies
MPH van den Broek, F Groenendaal… - Clinical …, 2010 - Springer
… pH of 7.4 and a pCO 2 of 5.3 kPa (40 mmHg) [pH-stat].[44] In contrast, in the alpha-stat method,
the blood pH is adjusted to a pH of … and adverse effects, the pH-stat method seems to be …
the blood pH is adjusted to a pH of … and adverse effects, the pH-stat method seems to be …
Allogeneic mesenchymal stem cells stimulate cartilage regeneration and are safe for single-stage cartilage repair in humans upon mixture with recycled autologous …
…, MPH van den Broek, R Nizak, MHP van Rijen… - Stem …, 2017 - academic.oup.com
Traditionally, mesenchymal stem cells (MSCs) isolated from adult bone marrow were
described as being capable of differentiating to various lineages including cartilage. Despite …
described as being capable of differentiating to various lineages including cartilage. Despite …
Clinical management of seizures in newborns: diagnosis and treatment
LGM van Rooij, MPH van den Broek, CMA Rademaker… - Pediatric Drugs, 2013 - Springer
Neonatal seizures can be classified as tonic, clonic, myoclonic, and subtle. A clinical diagnosis
is not easy as seizures are usually subtle in neonates. In the majority of newborn infants …
is not easy as seizures are usually subtle in neonates. In the majority of newborn infants …
[HTML][HTML] Intrathecal trastuzumab versus alternate routes of delivery for HER2-targeted therapies in patients with HER2+ breast cancer leptomeningeal metastases
…, S Hofer, W Jacot, HJ Stemmler, MPH van den Broek… - The Breast, 2023 - Elsevier
Background Patients with HER2+ breast cancer (BC) frequently develop leptomeningeal
metastases (LM). While HER2-targeted therapies have demonstrated efficacy in the …
metastases (LM). While HER2-targeted therapies have demonstrated efficacy in the …
How systemic inflammation modulates adenosine metabolism and adenosine receptor expression in humans in vivo
Objective: Adenosine modulates inflammation and prevents associated organ injury by
activation of its receptors. During sepsis, the extracellular adenosine concentration increases …
activation of its receptors. During sepsis, the extracellular adenosine concentration increases …
[HTML][HTML] Uremic solutes in chronic kidney disease and their role in progression
…, AD van Zuilen, PJ Blankestijn, PH van den Broek… - PLoS …, 2016 - journals.plos.org
… van den Broek, … van den Broek, … However, compared to the patients in the studies by
Niewczas et al. and Van der Kloet et al., our patients had more advanced CKD. Other metabolic …
Niewczas et al. and Van der Kloet et al., our patients had more advanced CKD. Other metabolic …
[HTML][HTML] Impact of metformin on endothelial ischemia-reperfusion injury in humans in vivo: a prospective randomized open, blinded-endpoint study
…, RD Kengen, GA Rongen, PH van den Broek… - PloS one, 2014 - journals.plos.org
… van den Broek, … van den Broek, … Citation: El Messaoudi S, Schreuder TH, Kengen RD,
Rongen GA, van den Broek PH, Thijssen DHJ, et al. (2014) Impact of Metformin on Endothelial …
Rongen GA, van den Broek PH, Thijssen DHJ, et al. (2014) Impact of Metformin on Endothelial …
Lidocaine response rate in aEEG‐confirmed neonatal seizures: retrospective study of 413 full‐term and preterm infants
…, L Hellström‐Westas, MPH Van Den Broek… - …, 2016 - Wiley Online Library
… study by van den Broek et al.,16 all infants received lidocaine as third-line AED, possibly
explaining the higher response rate. Furthermore, all infants in the study by van den Broek et al.…
explaining the higher response rate. Furthermore, all infants in the study by van den Broek et al.…