[HTML][HTML] Characterization of placental bikunin, a novel human serine protease inhibitor

…, JE Brown, RC Das, SO Roczniak, PP Tamburini - Journal of Biological …, 1997 - ASBMB
We reported previously the cloning of a novel human serine protease inhibitor containing two
Kunitz-like domains, designated as placental bikunin, and the subsequent purification of a …

Therapeutic mechanism and efficacy of the antibody–drug conjugate BAY 79-4620 targeting human carbonic anhydrase 9

…, A Voznesensky, G Ranges, PP Tamburini - Molecular Cancer …, 2012 - AACR
… The top 10 Fabs disclosed in Tamburini and colleagues (25) with respect to selective
binding and internalization by CAIX-expressing cancer cell lines were converted to full-length …

Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of …

GG Gibson, TC Orton, PP Tamburini - Biochemical Journal, 1982 - portlandpress.com
Hypolipidaemic drugs induce peroxisomal proliferation in the liver and many induce the
formation of the hepatic endoplasmic reticulum in general and the formation of cytochrome P-…

[HTML][HTML] Identification and cloning of human placental bikunin, a novel serine protease inhibitor containing two Kunitz domains

…, G Davis, DK Muller, JM Greve, PP Tamburini - Journal of Biological …, 1997 - ASBMB
Interrogation of the public expressed sequence tag (EST) data base with the sequence of
preproaprotinin identified ESTs encoding two potential new members of the Kunitz family of …

Enzymatic peptidyl. alpha.-amidation proceeds through formation of an. alpha.-hydroxyglycine intermediate

SD Young, PP Tamburini - Journal of the American Chemical …, 1989 - ACS Publications
Tamburini … N.; Tamburini, P. P.;Consalvo, A. P.; Young, S. …

Multiple forms of hepatic cytochrome P‐450: Purification, characterisation and comparison of a novel clofibrate‐induced isozyme with other major forms of cytochrome …

PP Tamburini, HA Masson, SK Bains… - European journal of …, 1984 - Wiley Online Library
In the present studies, a novel form of highly purified cytochrome P‐450 (cytochrome P‐452)
isolated from the hepatic microsomes of clofibrate‐pretreated rats has been compared to …

Cytochrome P-450 spin state: inorganic biochemistry of haem iron ligation and functional significance

GG Gibson, PP Tamburini - Xenobiotica, 1984 - Taylor & Francis
1. Haem ligation in cytochrome P-450 has been reviewed and the nature of the fifth and
sixth ligands of the haemoprotein in the ferric low-spin, ferric high-spin, ferrous and ferrous-…

[HTML][HTML] Chemical characterization of protein-protein interactions between cytochrome P-450 and cytochrome b5.

PP Tamburini, RE White, JB Schenkman - Journal of Biological Chemistry, 1985 - Elsevier
Native cytochrome b5 interacts with either RLM5 or LM2 to form tight equimolar complexes (Kd
= 250 and 540 nM, respectively) in which the content of high spin cytochrome P-450 was …

17β‐Hydroxysteroid Dehydrogenases in Human Bone Cells

…, WF Lathrop, DR Bertolini, PP Tamburini - Journal of Bone and …, 1998 - academic.oup.com
Interconversion of estrogens by osteoblasts may play a role in regulating bone mass. As a
first step toward exploring this possibility, we investigated the expression and activity of 17β‐…

Differences in the mechanism of functional interaction between NADPH-cytochrome P-450 reductase and its redox partners.

PP Tamburini, JB Schenkman - Molecular pharmacology, 1986 - ASPET
Selective methylamidation of NADPH-cytochrome P-450 reductase (EC 1.6.2.4) carboxyl
groups was used to assess the relative importance of these groups in the enzyme-catalyzed …