Transglutaminases catalyze the posttranslational modification of proteins by transamidation
of available glutamine residues. This action results primarily in the formation of ∊‐(γ‐…

Late in the terminal differentiation of epidermis and cultured epidermal cells, a protein
envelope located beneath the plasma membrane becomes crosslinked by cellular …

A small proportion of the protein of stratum corneum of human epidermal callus is insoluble
even when boiled in solutions containing sodium dodecylsulfate and a reducing agent. This …

… of involucrin were determined by Elisa modification (Parenteau and Rice, unpublished
data) of a radioimmunoassay method (Cline and Rice, 1963). (A) Dependence of acid …

… Cline PR, Rice RH: lnvolucrin and envelope competence in human keratinocytes: modulation
by hydroconisone, retinyl acetate and growth arrest. Cancer Res 4:3:3203-3207, 1983 16. …

Reductive methylation has little or no detectable effect on the catalytic or physicochemical
properties of bovine trypsin but reduces its susceptibility to autolysis. Increased stability after …

Human identification from biological material is largely dependent on the ability to characterize
genetic polymorphisms in DNA. Unfortunately, DNA can degrade in the environment, …

Proteomic technologies, such as yeast twohybrid, mass spectrometry (MS), protein/peptide
arrays and fluorescence microscopy, yield multi-dimensional data sets, which are often quite …

The human hair proteome was investigated using two-dimensional LC-MS/MS. Among the
343 identified proteins, 70 were detected in high relative abundance, including keratin …

The evolution of amniotes has involved major molecular innovations in the epidermis. In
particular, distinct structural proteins that undergo covalent cross-linking during cornification of …