The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci

…, IC Gunsalus, EF Johnson, B Kemper, W Levin… - Dna, 1989 - liebertpub.com
In this update we provide a list of the 71 P450 genes and the four P450 pseudogenes that
have been characterized as of September 30, 1988. The chromosomal locations of many of …

[HTML][HTML] Proton beam therapy

WP Levin, H Kooy, JS Loeffler, TF Delaney - British journal of Cancer, 2005 - nature.com
Conventional radiation therapy directs photons (X-rays) and electrons at tumours with the
intent of eradicating the neoplastic tissue while preserving adjacent normal tissue. Radiation-…

PCBs: structure–function relationships and mechanism of action

…, PE Thomas, DE Ryan, LM Reik, W Levin… - Environmental …, 1985 - ehp.niehs.nih.gov
… Botelho, LH, Ryan, DE, and Levin, W. Amino acid compositions and partial amino acid
sequences of three highly purified forms of liver microsomal cytochrome P-450 from rats treated …

Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neu Oncogene

DJ Slamon, GM Clark, SG Wong, WJ Levin, A Ullrich… - science, 1987 - science.org
The HER-2/neu oncogene is a member of the erbB-like oncogene family, and is related to,
but distinct from, the epidermal growth factor receptor. This gene has been shown to be …

Studies of the HER-2/neu Proto-Oncogene in Human Breast and Ovarian Cancer

…, LA Jones, JA Holt, SG Wong, DE Keith, WJ Levin… - Science, 1989 - science.org
Carcinoma of the breast and ovary account for one-third of all cancers occurring in women
and together are responsible for approximately one-quarter of cancer-related deaths in …

The P450 gene superfamily: recommended nomenclature

…, IC Gunsalus, EF Johnson, B Kemper, W Levin… - Dna, 1987 - liebertpub.com
A nomenclature for the P450 gene superfamily is proposed based on evolution. Recommendations
include Roman numerals for distinct gene families, capital letters for subfamilies, and …

An improved staining procedure for the detection of the peroxidase activity of cytochrome P-450 on sodium dodecyl sulfate polyacrylamide gels

PE Thomas, D Ryan, W Levin - Analytical biochemistry, 1976 - Elsevier
The use of 3,3′,5,5′-tetramethylbenzidine-H 2 O 2 as a stain for the peroxidase activity of
cytochrome P-450 (or cytochrome P-450 in sodium dodecyl sulfate polyacrylamide gels is …

Oxygenation predicts radiation response and survival in patients with cervix cancer

…, M Pintilie, A Sun, W Chapman, W Levin… - Radiotherapy and …, 1998 - Elsevier
Background and purpose: Hypoxia appears to be an important factor in predicting tumor
relapse following radiation therapy. This study measured oxygenation prior to treatment in …

Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic …

…, P He, N Angra, AK Gupta, W Levin… - The Lancet …, 2020 - thelancet.com
Background Survival outcomes are poor for patients with metastatic urothelial carcinoma
who receive standard, first-line, platinum-based chemotherapy. We assessed the overall …

Tumor hypoxia has independent predictor impact only in patients with node-negative cervix cancer

…, M Milosevic, D Hedley, M Pintilie, W Levin… - Journal of Clinical …, 2002 - ascopubs.org
PURPOSE: This prospective clinical study was begun in 1994 to validate the independent
prognostic impact of tumor hypoxia in patients with cervix cancer treated with definitive …