Absorption, distribution, metabolism, and excretion of 2, 2-bis (bromomethyl)-1, 3-propanediol in male fischer-344 rats

SI Hoehle, GA Knudsen, JM Sanders, IG Sipes - Drug Metabolism and …, 2009 - ASPET
2, 2-Bis (bromomethyl)-1, 3-propanediol (BMP) is a brominated flame retardant, previously
shown to be a multisite carcinogen in experimental animals. Studies were performed to …

Kidney and urinary bladder lesions in F344N rats and B6C3F1 mice after 13 weeks of 2, 2-bis (bromomethyl)-1, 3-propanediol administration

MR Elwell, JK Dunnick, HR Brown… - … and Applied Toxicology, 1989 - Elsevier
Thirteen-week toxicity studies of the flame retardant 2, 2-bis (bromomethyl)-1, 3-propanediol
(BMP; dibromoneopentyl glycol; FR-1138; CAS No. 329690-0) were conducted in male and …

Disposition of the emerging brominated flame retardant, 2-ethylhexyl 2, 3, 4, 5-tetrabromobenzoate, in female SD rats and male B6C3F1 mice: effects of dose, route …

GA Knudsen, JM Sanders… - Toxicological Sciences, 2016 - academic.oup.com
2-Ethylhexyl-2, 3, 4, 5-tetrabromobenzoate (EH-TBB; MW 549.92 g/mol; CAS 183658-27-7)
is a brominated component of flame retardant mixtures used as substitutes for some PBDEs …

Toxicity and Carcinogenicity of 2,3-Dibromo-1-propanol in F344/N Rats and B6C3F1 Mice

SL Eustis, JK Haseman, WF Mackenzie… - Toxicological …, 1995 - academic.oup.com
Dibromo-1-propanol is a metabolite of the flame retardant tris (2, 3-dibromopropyl)
phosphate, previously shown to be a mutagen and carcinogen in experimental animals …

Carcinogenic activity of the flame retardant, 2, 2-bis (bromomethyl)-1, 3-propanediol in rodents, and comparison with the carcinogenicity of other NTP brominated …

JK Dunnick, JE Heath, DR Farnell… - Toxicologic …, 1997 - journals.sagepub.com
Several brominated chemicals have been shown to be multisite-multispecies carcinogens in
laboratory animals, and in this paper we report that the flame retardant, 2, 2-bis …

The effects of dose, route, and repeated dosing on the disposition and kinetics of tetrabromobisphenol A in male F-344 rats

RK Kuester, AM Sólyom, VP Rodriguez… - Toxicological …, 2007 - academic.oup.com
Studies were conducted to characterize the metabolic and dispositional fate of 14C–
tetrabromobisphenol A (TBBPA)—a commonly used brominated flame retardant, in male …

Absorption, distribution, metabolism and excretion of intravenously and orally administered tetrabromobisphenol A [2, 3-dibromopropyl ether] in male Fischer-344 rats

GA Knudsen, LM Jacobs, RK Kuester, IG Sipes - Toxicology, 2007 - Elsevier
Tetrabromobisphenol A bis [2, 3-dibromopropyl ether], 2, 2-bis [3, 5-dibromo-4-(2, 3-
dibromopropoxy) phenyl] propane is a brominated flame retardant with substantial US …

Disposition of the emerging brominated flame retardant, bis (2-ethylhexyl) tetrabromophthalate, in female Sprague Dawley rats: effects of dose, route and repeated …

GA Knudsen, JM Sanders, LS Birnbaum - Xenobiotica, 2017 - Taylor & Francis
Bis (2-ethylhexyl)-tetrabromophthalate (BEH-TEBP; CAS No. 26040-51-7; PubChem CID:
117291; MW 706.15 g/mol, elsewhere: TeBrDEPH, TBPH, or BEHTBP) is used as an …

In vitro glucuronidation of 2, 2-bis (bromomethyl)-1, 3-propanediol by microsomes and hepatocytes from rats and humans

G Rad, SI Hoehle, RK Kuester, IG Sipes - Drug Metabolism and Disposition, 2010 - ASPET
2, 2-Bis (bromomethyl)-1, 3-propanediol (BMP) is a brominated flame retardant used in
unsaturated polyester resins. In a 2-year bioassay BMP was shown to be a multisite …

An ADME study with 2, 2′, 4, 4′, 5, 6′-hexabromodiphenyl ether (BDE-154) in male Sprague-Dawley rats

H Hakk, J Huwe, G Larsen - Organohalogen Compd, 2005 - ars.usda.gov
The polybrominated diphenyl ethers (PBDEs) are among the most abundant brominated
flame retardants in use. Furthermore, a particular subset of five PBDEs are known to be …