Abstract
5-p-Carboxybenzoyl-1-methylpyrrole-2-acetic acid has been identified in the rat, monkey, and man as the major urinary metabolite of tolmetin, a new nonsteroidal anti-inflammatory agent. Conjugation of tolmetin, a major mode of disposition in man and monkey, was not observed in the rat.
Footnotes
- Received January 27, 1975.
- Copyright © 1975 by The American Society for Pharmacology and Experimental Therapeutics