Supplemental Data
Files in this Data Supplement:
- Supplemental Data -
Materials and Methods
- Supplemental Table 1 -
In vitro metabolism of compound-K, 20(S)-protopanaxadiol, and 20(S)-protopanaxatriol using human liver microsomes, rat liver microsomes or rat colon microsomes
- Supplemental Table 2 -
Comparative enzymatic kinetics of human liver microsomes and rat liver microsomes toward the oxidation of 20(S)-protopanaxadiol or 20(S)-protopanaxatriol
- Supplemental Table 3 -
Human plasma pharmacokinetics and urinary excretion data of ginsenosides and their major metabolites after a single p.o. dose of Sanqi-extract at 90 ml/subject
- Supplemental Table 4 -
Human plasma pharmacokinetics and urinary excretion data of ginsenosides and their major metabolites after a single p.o. dose of Sanqi-extract at 180 ml/subject.
- Supplemental Table 5 -
Human plasma pharmacokinetics and urinary excretion data of ginsenosides and their major metabolites after a single p.o. dose of Sanqi-extract at 270 ml/subject
- Supplemental Figure 1 -
Tissue distribution and biliary excretion profiles of 20(S)-protopanaxadiol, 20(S)-protopanaxatriol, and their metabolites in rats