Data Supplement
Files in this Data Supplement:
- Supplemental Data -
Supplemental Protein Sequences
Supplemental Figure 1 - ELISA analysis of FST-Fc (open circles), FST-Delta-HBS-Fc (open squares), MV9 (open triangles) and MV12 (open diamonds) interactions with surface coated Heparin Sulfate
Supplemental Figure 2 - Comparison of the relative abundance of the glycosylation occupancy, antennary and structural differences in each of the N-linked sites in MV9 (grey bars) and MV12 (black bars)
Supplemental Figure 3 - Analysis of the variability in the average antennary structure (A) and percent of asiaylated carbohydrate (B) of the three site-specific N-linked carbohydrates found in the FST-Fc proteins
Supplemental Figure 4 - Relative comparison of average amounts of carbohydrate content terminating in (A) galactose and (B) n-acetylglucosamine/mannose
Supplemental Figure 5 - Changes in molar carbohydrate content of carbohydrates terminating in sialic acid (open circles), galactose (open diamonds) and nacetylglucosamine (open squares) of samples extracted from serum samples taken from the SCID pharmacokinetic study