Data Supplement
Files in this Data Supplement:
- Supplemental Data -
Supplemental Table 1 - Input parameters of the victim drugs (substrates) used in simulations
Supplemental Table 2 - Input parameters of the perpetrator drugs (inducers) used in simulations
Supplemental Table 3 - Meta-analysis of studies where midazolam (victim drug) was administered orally
Supplemental Figure 1 - Simulated (line) and observed (open circles) mean systemic concentration time profiles of inducers after multiple dosing...
Supplemental Figure 2 - Simulated (open) and reported (black) fmCYP3A4 (A) and FG (B) values for the victim drugs used in these analyses
References