Data Supplement
Files in this Data Supplement:
- Supplemental Data -
Analytical instrumentation and general aspects of bioanalysis
Supplemental Table 1 - Bioanalytical analysis details
Supplemental Table 2 - Parameters used for PBPK modeling
Supplemental Table 3 - Comparison of the AUC ratio predicted by the quinidine model under different dosing simulations to clinical interaction studies
Supplemental Figure 1 - Predicted and observed plasma concentration-time profiles of A) bufuralol (60 mg) and B) dextromethorphan (30 mg)
References