Data Supplement
Files in this Data Supplement:
- Supplemental Figures -
Supplemental Figure 1 - 1H NMR spectrum of Met2
Supplemental Figure 2 - ESI-TOF HRMS of Met2
Supplemental Figure 3 - MS spectra of the metabolites identified in HLM compared to the analytic standards of Met1 and Met2
Supplemental Figure 4 - Kinetics of metabolite formation from CINPA1 or Met1 in recombinant human P450s
Supplemental Figure 5 - Metabolism of midazolam in human recombinant CYP3A4 or HLM in the presence of inhibitors