Data Supplement
Files in this Data Supplement:
- Supplemental Data -
Supplemental Table 1 - Tissue to plasma ratios of pefloxacin in selected tissues following a single 25 mg/kg oral dose administration of 14Cpefloxacin or pefloxacin to Sprague Dawley rats
Supplemental Table 2 - Summary of protonated molecular ion, observed mass, elemental composition, characteristic product ions and proposed structures of metabolites of pefloxacin
Supplemental Scheme 1 - Synthesis of 14Cpefloxacin
Supplemental Figure 1 - Correlation between nominal and NMR-measured concentrations of pefloxacin in rat plasma Panel A, urine Panel B, bile Panel C and feces Panel D