Data Supplement
- Supplemental Data -
Supplemental Table 1: Summary of IC50 values from early screening studies for P450 inhibition by imetelstat in pooled human liver microsomes (HLM).
Supplemental Table 2: Summary of percent residual activity values for P450 inhibition by imetelstat in cryopreserved human hepatocytes (CHH).
Supplemental Figure 1: IC50 shift experiment to assess the time-dependent inhibition (TDI) potential of imetelstat on CYP2C8 in cryopreserved human hepatocytes (CHH).