Data Supplement
- Supplemental Figures -
Supplementary Figure 1 - Kinetics of carbazeran 4-oxidation by liver cytosol (A) and recombinant human AOX1 (B).
Supplementary Figure 2 - Chromatographic profile of carbazeran and its metabolites in urine after oral administration of carbazeran to humanized-liver mice (A) and control mice (B).
Supplementary Figure 3 - The MS/MS spectra of carbazeran metabolites M2 (A), M3 (B), and M4 (C).