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Drug Metabolism & Disposition

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    Investigating the Utility of Humanized PXR-CAR-CYP3A4/7 Mouse Model to Assess CYP3A-Mediated Induction
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    Drug Metabolism and Disposition April 16, 2021, DMD-AR-2021-000439; DOI: https://doi.org/10.1124/dmd.121.000439
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    Drug Metabolism and Disposition April 6, 2021, DMD-AR-2021-000367; DOI: https://doi.org/10.1124/dmd.121.000367
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    Drug Metabolism and Disposition April 2, 2021, DMD-AR-2021-000356; DOI: https://doi.org/10.1124/dmd.121.000356
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    Pharmacokinetic and biochemical profiling of Sodium Dichloroacetate in pregnant ewes and fetuses
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    Drug Metabolism and Disposition April 2, 2021, DMD-AR-2020-000330; DOI: https://doi.org/10.1124/dmd.120.000330
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    Metabolism and Mass Balance of the Novel Nonsteroidal Androgen Receptor Inhibitor Darolutamide in Humans
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About Drug Metabolism & Disposition

DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

Current issue

Drug Metabolism and Disposition: 49 (5)
Drug Metabolism and Disposition
Vol. 49, Issue 5
1 May 2021
  • Table of Contents
  • About the Cover
  • Index by author

DMD is published continuously. Articles are added as they are ready and assigned to monthly issues. Check this site for new content or sign up for content alerts.

EDITOR'S CHOICE ARTICLES FOR MAY:

  • In Vivo Functional Effects of CYP2C9 M1L, a Novel and Common Variant in the Yup’ik Alaska Native Population - open access
  • Tertiary Oxidation of Deoxycholate Is Predictive of CYP3A Activity in Dogs
  • SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function - open access
  • Absorption, Metabolism, and Excretion, In Vitro Pharmacology, and Clinical Pharmacokinetics of Ozanimod, a Novel Sphingosine 1-Phosphate Receptor Modulator - open access
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  • Pharmacokinetics and Disposition of Biologics
  • Physiology of the Neonatal Gastrointestinal System
  • Tissue Drug Concentrations: Beyond the Free Drug Hypothesis
  • Metabolism and Disposition of Volanesorsen across Species
  • Transporter-Mediated Drug-Drug Interactions for E7766
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