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DMD Marks Its 50th Anniversary with Celebration Collection

Special Section Focusing on Drug Metabolism and Precision Medicine - freely accessible through October 31, 2023

Special Section on Perspective on Drug Metabolism and Disposition- Part 1 by DMD Associate Editors - freely accessible through December 31, 2023

Latest Fast Forward Articles

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Activation of CYP3A by ABC phenomenon potentiates the hepatocellular carcinoma-targeting therapeutic effects of PEGylated anticancer prodrug liposomes
Xue Zhang, Jianquan Pan, Xi Ye, Yunna Chen, Lei Wang, Xiangyun Meng, Weidong Chen and Fengling Wang

Drug Metabolism and Disposition September 29, 2023, DMD-AR-2023-001496; DOI: https://doi.org/10.1124/dmd.123.001496
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The Effects of Drug Exposure and SNPs on Aaptinib-induced Severe Toxicities in Solid Tumors
Youhao Chen, Yaobin Lin, Shaoxing Guan, Zerui Zhao, Daren Lin, Jin Guan, Chengzhi Zhou, Junling Liu, Xiaolong Cao, Zhichao Lin, Diyao Chen, Jianbiao Shang, Weijian Zhang, Huohui Chen, Likun Chen, Shudong Ma, Lijia Gu, Jian Zhao, Min Huang, Xueding Wang and Hao Long

Drug Metabolism and Disposition September 29, 2023, DMD-AR-2023-001428; DOI: https://doi.org/10.1124/dmd.123.001428
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Innovations, Opportunities and Challenges for Predicting Alteration in Drug Metabolizing Enzymes and Transporters Activity in Specific Populations
Paresh P. Chothe, Vikram Arya, Bhagwat Prasad, Diane Ramsden and Kunal Taskar

Drug Metabolism and Disposition September 29, 2023, DMD-COM-2023-001453; DOI: https://doi.org/10.1124/dmd.123.001453
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Functional Characterization of 29 Cytochrome P450 4F2 Variants Identified in a Population of 8,380 Japanese Subjects and Assessment of Arachidonic Acid ω-Hydroxylation
Yu SATO, Eiji Hishinuma, Shuki YAMAZAKI, Akiko Ueda, Masaki KUMONDAI, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka

Drug Metabolism and Disposition September 29, 2023, DMD-AR-2023-001389; DOI: https://doi.org/10.1124/dmd.123.001389
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Differential Effects of Clotrimazole on X-Ray Crystal Structures of Human Cytochrome P450 (CYP) 3A5 and 3A4
Mei-Hui Hsu and Eric F. Johnson

Drug Metabolism and Disposition September 28, 2023, DMD-AR-2023-001464; DOI: https://doi.org/10.1124/dmd.123.001464
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Identification and validation of active ingredient in cerebrotein hydrolysate-I based on pharmacokinetic and pharmacodynamic studies
Huimin Guo, Huizhu Yang, Chanjuan Di, Feng Xu, Hong Sun, Yexin Xu, Huafang Liu, Linlin Wu, Ke Ding, Tingting Zhang, Lin Xie, Guangji Wang and Yan Liang

Drug Metabolism and Disposition September 27, 2023, DMD-AR-2023-001443; DOI: https://doi.org/10.1124/dmd.123.001443

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DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

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