Home | Drug Metabolism & Disposition

Advertisement

ASPET President-Elect Namandje N. Bumpus, PhD Elected to the National Academy of Medicine

Call for Abstracts - ASPET 2023 Annual Meeting - DUE DECEMBER 8

Special Section on Bile Acids, Drug Metabolism, and Toxicity - freely accessible through October 31, 2022

Special Section on Drug Metabolism in Liver injury and Regeneration - freely accessible through December 31, 2022

Special Section on Pharmacokinetics and ADME of Biological Therapeutics - freely accessible through January 31, 2023

Special Section on Drug Metabolism and Regulation - freely accessible through February 28, 2023

Special Section on New Era of Transporter Science: Unraveling the Functional Role of Orphan Transporters - freely accessible through March 31, 2023

Special Section on Mechanistic and Translational Research on Transporters in Toxicology - freely accessible through April 30, 2023

Latest Fast Forward Articles

You have access
Quantification of accurate composition and total abundance of homologous proteins by conserved-plus-surrogate peptide (CPSP) approach: Quantification of UDP glucuronosyltransferases in human tissues
Deepak Ahire, Mitesh Patel, Sujal V Deshmukh and Bhagwat Prasad

Drug Metabolism and Disposition November 29, 2022, DMD-AR-2022-001155; DOI: https://doi.org/10.1124/dmd.122.001155
You have access
Maternal and Fetal Exposure to (-)-Δ⁹-tetrahydrocannabinol and Its Major Metabolites in Pregnant Mice Is Differentially Impacted by P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP)
Xin Chen, Jashvant D. Unadkat and Qingcheng Mao

Drug Metabolism and Disposition November 29, 2022, DMD-AR-2022-001110; DOI: https://doi.org/10.1124/dmd.122.001110
You have access
Cell and tissue specific metabolism of nucleoside and nucleotide drugs: case studies and implications for precision medicine
Elaine E To

Drug Metabolism and Disposition November 29, 2022, DMD-MR-2022-000856; DOI: https://doi.org/10.1124/dmd.122.000856
You have access
Hydroxychloroquine is metabolized by CYP2D6, CYP3A4, and CYP2C8, and inhibits CYP2D6, while its metabolites also inhibit CYP3A in vitro
Marie-Noëlle Paludetto, Mika Kurkela, Helinä Kahma, Janne T. Backman, Mikko Niemi and Anne M. Filppula

Drug Metabolism and Disposition November 29, 2022, DMD-AR-2022-001018; DOI: https://doi.org/10.1124/dmd.122.001018
You have access
Multidisciplinary Insights into the Structure-Function Relationship of the CYP2B6 Active Site
Ethan D. Angle and Philip M Cox

Drug Metabolism and Disposition November 23, 2022, DMD-MR-2022-000853; DOI: https://doi.org/10.1124/dmd.122.000853
You have access
Functional characterization of 12 dihydropyrimidinase allelic variants in Japanese individuals for the prediction of 5-fluorouracil treatment-related toxicity
Eiji Hishinuma, Yoko Narita, Evelyn Marie Gutiérrez Rico, Akiko Ueda, Kai Obuchi, Yoshikazu Tanaka, Sakae Saito, Shu Tadaka, Kengo Kinoshita, Masamitsu Maekawa, Nariyasu Mano, Tomoki Nakayoshi, Akifumi Oda, Noriyasu Hirasawa and Masahiro Hiratsuka

Drug Metabolism and Disposition November 22, 2022, DMD-AR-2022-001045; DOI: https://doi.org/10.1124/dmd.122.001045

About Drug Metabolism & Disposition

DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

For an alternate route to this Journal use this URL: http://intl-dmd.aspetjournals.org