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HLM-beads: Rapid assessment of non-specific binding to human liver microsomes using magnetizable beads
Ting Wang, Andrea Whitcher-Johnstone, Monica Keith-Luzzi and Tom S. Chan

Drug Metabolism and Disposition September 24, 2021, DMD-AR-2021-000575; DOI: https://doi.org/10.1124/dmd.121.000575
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Ontogeny of Small Intestinal Drug Transporters and Metabolizing Enzymes Based on Targeted Quantitative Proteomics
Márton Kiss, Richard Mbasu, Johan Nicolaï, Karin Barnouin, Apoorva Kotian, Miriam Geerthe Mooij, Nico Kist, Rene M.H. Wijnen, Anna-Lena Ungell, Paul Cutler, Frans G.M. Russel and Saskia N. de Wildt

Drug Metabolism and Disposition September 21, 2021, DMD-AR-2021-000559; DOI: https://doi.org/10.1124/dmd.121.000559
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Exogenous Drug Disposition as a Diagnostic Biomarker Strategy for Non-Alcoholic Steatohepatitis
Solène MARIE, David K.K. TRIPP and Nathan J. CHERRINGTON

Drug Metabolism and Disposition September 16, 2021, DMD-MR-2021-000413; DOI: https://doi.org/10.1124/dmd.121.000413
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Complex Cytochrome P450 kinetics due to multisubstrate binding and sequential metabolism. Part 1. Theoretical considerations.
Zeyuan Wang, Erickson M. Paragas, Swati Nagar and Ken Korzekwa

Drug Metabolism and Disposition September 9, 2021, DMD-AR-2021-000553; DOI: https://doi.org/10.1124/dmd.121.000553
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Complex Cytochrome P450 kinetics due to multisubstrate binding and sequential metabolism. Part 2. Modeling of experimental data
Erickson M. Paragas, Zeyuan Wang, Ken Korzekwa and Swati Nagar

Drug Metabolism and Disposition September 9, 2021, DMD-AR-2021-000554; DOI: https://doi.org/10.1124/dmd.121.000554
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Cannabinoid metabolites as inhibitors of major hepatic CYP450 enzymes, with implications for cannabis-drug interactions
Shamema Nasrin, Christy J.W. Watson, Yadira X Perez-Paramo and Philip Lazarus

Drug Metabolism and Disposition September 7, 2021, DMD-AR-2021-000442; DOI: https://doi.org/10.1124/dmd.121.000442

About Drug Metabolism & Disposition

DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

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