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Special Section on Natural Products: Experimental Approaches to Elucidate Disposition Mechanisms and Predict Pharmacokinetic Drug Interactions
Freely Accessible through Dec. 31

Dr. Xinxin Ding Chosen to Be Next DMD Editor

Dr. Rob Foti Named New Associate Editor

Latest Fast Forward Articles

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Effect of Gender and Various Diets on Bile Acid Profile and Related Genes in Mice
Chong Ma, Ying Guo and Curtis D. Klaassen

Drug Metabolism and Disposition October 22, 2020, DMD-AR-2020-000166; DOI: https://doi.org/10.1124/dmd.120.000166
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Down-regulation of CYP1A2, CYP2B6, and CYP3A4 in human hepatocytes by prolyl hydroxylase domain 2 inhibitors via hypoxia-inducible factor-α stabilization
Hiroki Takano, Jun-ichi Yamaguchi, Sota Kato, Makoto Hamada, Mika Tada and Hiromi Endo

Drug Metabolism and Disposition October 21, 2020, DMD-AR-2020-000124; DOI: https://doi.org/10.1124/dmd.120.000124
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Characterization of the human intestinal drug transport with Ussing chamber system incorporating freshly-isolated human jejunum
Kazuyoshi Michiba, Kazuya Maeda, Kou Kurimori, Tsuyoshi Enomoto, Osamu Shimomura, Tomoyo Takeuchi, Hiroyuki Nishiyama, Tatsuya Oda and Hiroyuki Kusuhara

Drug Metabolism and Disposition October 21, 2020, DMD-AR-2020-000138; DOI: https://doi.org/10.1124/dmd.120.000138
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Histone Methyltransferase G9a Regulates Expression of Nuclear Receptors and Cytochrome P450 Enzymes in HepaRG Cells at Basal Level and in Fatty Acid Induced Steatosis.
Parimal Pande, Xiao-bo Zhong and Warren W. Ku

Drug Metabolism and Disposition October 19, 2020, DMD-AR-2020-000195; DOI: https://doi.org/10.1124/dmd.120.000195
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Prediction of Transporter-Mediated Rosuvastatin Hepatic Uptake Clearance and Drug Interaction in Humans Using Proteomics-Informed REF Approach
Vineet Kumar, Mengyue Yin, Kazuya Ishida, Laurent Salphati, Cornelis E.C.A. Hop, Christopher Rowbottom, Guangqing Xiao, Yurong Lai, Anita Mathias, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Zsuzsanna Nerada, Nóra Szilvásy, Scott Heyward and Jashvant D. Unadkat

Drug Metabolism and Disposition October 13, 2020, DMD-AR-2020-000204; DOI: https://doi.org/10.1124/dmd.120.000204
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Development of a pharmacokinetic model of transplacental transfer of metformin to predict in vivo fetal exposure
Ken Kurosawa, Koji Chiba, Saki Noguchi, Tomohiro Nishimura and Masatoshi Tomi

Drug Metabolism and Disposition October 13, 2020, DMD-AR-2020-000127; DOI: https://doi.org/10.1124/dmd.120.000127

About Drug Metabolism & Disposition

DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

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