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Quantitative prediction of drug-drug interactions caused by CYP3A induction using endogenous biomarker 4β-hydroxycholesterol
Hiroaki Takubo, Toshio Taniguchi and Yukihiro Nomura

Drug Metabolism and Disposition October 10, 2024, DMD-AR-2024-001876; DOI: https://doi.org/10.1124/dmd.124.001876
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Utilization of a Human Liver Tissue Chip for Drug-Metabolizing Enzyme Induction Studies of Perpetrator and Victim Drugs
Shivam Ohri, Paarth Parekh, Lauren Nichols, Shiny Amala Priya Rajan and Murat Cirit

Drug Metabolism and Disposition October 7, 2024, DMD-AR-2023-001497; DOI: https://doi.org/10.1124/dmd.124.001497
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Early prediction and impact assessment of CYP3A4-related drug-drug interactions for small molecule anti-cancer drugs using human-CYP3A4-transgenic mouse models
David Damoiseaux, Jos H. Beijnen, Alwin D.R. Huitema and Thomas P.C. Dorlo

Drug Metabolism and Disposition October 3, 2024, DMD-AR-2023-001530; DOI: https://doi.org/10.1124/dmd.123.001530
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CYP and non-CYP drug metabolizing enzyme families exhibit differential sensitivities towards pro-inflammatory cytokine modulation
Laura M. de Jong, Chandan Harpal, Dirk-Jan van den Berg, Menno Hoekstra, Nienke J Peter, Robert Rissmann, Jesse J Swen and Martijn L. Manson

Drug Metabolism and Disposition September 30, 2024, DMD-AR-2024-001867; DOI: https://doi.org/10.1124/dmd.124.001867
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Differential Selectivity of Human and Mouse ABCC4/Abcc4 for Arsenic Metabolites
Brayden D Whitlock, Yingze Ma, Gwenaelle Conseil, Alicia R O'Brien, Mayukh Banerjee, Diane P Swanlund, Z Ping Lin, Yao Wang, X. Chris Le, John D. Schuetz, Susan P.C. Cole and Elaine M. Leslie

Drug Metabolism and Disposition September 23, 2024, DMD-AR-2024-001852; DOI: https://doi.org/10.1124/dmd.124.001852
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Absorption, Distribution, Metabolism, and Excretion of Icenticaftor (QBW251) in Healthy Male Volunteers at Steady State and In Vitro Phenotyping of Major Metabolites
Ulrike Glaenzel, Felix Huth, Fabian Eggimann, Melissa Hackling, Luc Alexis Leuthold, Axel Meissner and Lidiya Bebrevska

Drug Metabolism and Disposition September 23, 2024, DMD-AR-2024-001751; DOI: https://doi.org/10.1124/dmd.124.001751

About Drug Metabolism & Disposition

DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

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