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ASPET 2024 Annual Meeting - Call for Abstracts - Submit by Dec. 7 for Posters/Awards/Talks. Submit by Feb. 22 for Posters Only

DMD Marks Its 50th Anniversary with Celebration Collection

Special Section on Perspective on Drug Metabolism and Disposition- Part 1 by DMD Associate Editors - freely accessible through December 31, 2023

Special Section on Mechanism-Based Predictive Methods in Drug Discovery and Development - freely accessible through April 30, 2024

Latest Fast Forward Articles

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Novel independent trans- and cis-genetic variants associated with CYP2D6 expression and activity in human livers
Dylan Smith, Bing He, Jian Shi, Hao-Jie Zhu and Xinwen Wang

Drug Metabolism and Disposition November 29, 2023, DMD-AR-2023-001548; DOI: https://doi.org/10.1124/dmd.123.001548
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Comparison of 1beta- and 5beta-hydroxylation of Deoxycholate and Glycodeoxycholate as In Vitro Index Reactions for CYP3A Activities
Cuitong Wang, Bin Cheng, Wei Wei, Lanlan Gui, Wushuang Zeng, Yutong Wang, Yixuan Wang, Qi Chen, Liang Xu, Jia Miao and Ke Lan

Drug Metabolism and Disposition November 29, 2023, DMD-AR-2023-001513; DOI: https://doi.org/10.1124/dmd.123.001513
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Deciphering the role of fatty acid metabolizing CYP4F11 in lung cancer and its potential as a drug target
Huiting Jia, Bjoern Brixius, Caleb Bocianoski, Sutapa Ray, David R. Koes and Simone Brixius-Anderko

Drug Metabolism and Disposition November 16, 2023, DMD-AR-2023-001463; DOI: https://doi.org/10.1124/dmd.123.001463
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Involvement of proton-coupled SLC49A4-mediated transport in the export of lysosomally trapped pyrilamine
Shogo Akino, Tomoya Yasujima, Rei Shibutani, Takahiro Yamashiro and Hiroaki Yuasa

Drug Metabolism and Disposition November 14, 2023, DMD-AR-2023-001354; DOI: https://doi.org/10.1124/dmd.123.001354
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Time-Dependent Inhibition of CYP1A2 by Stiripentol and Structurally Related Methylenedioxyphenyl Compounds via Metabolic Intermediate Complex Formation
Yasuhiro Masubuchi, Chieko Takahashi and Rina Gendo

Drug Metabolism and Disposition November 6, 2023, DMD-AR-2023-001511; DOI: https://doi.org/10.1124/dmd.123.001511
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The Role of Mechanistic Biomarkers in Understanding Acetaminophen Hepatotoxicity in Humans
Mitchell R. McGill

Drug Metabolism and Disposition November 2, 2023, DMD-MR-2023-001281; DOI: https://doi.org/10.1124/dmd.123.001281

About Drug Metabolism & Disposition

DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

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