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Hepatic Scaling Factors for In Vitro-In Vivo Extrapolation (IVIVE) of Metabolic Drug Clearance in Patients with Colorectal Cancer with Liver Metastasis
Areti-Maria Vasilogianni, Brahim Achour, Daniel Scotcher, Sheila Annie Peters, Zubida M. Al-Majdoub, Jill Barber and Amin Rostami-Hodjegan

Drug Metabolism and Disposition May 12, 2021, DMD-AR-2021-000359; DOI: https://doi.org/10.1124/dmd.121.000359
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Multiple Computational Approaches for Predicting Drug Interactions with Human Equilibrative Nucleoside Transporter 1
Siennah R. Miller, Thomas R. Lane, Kimberley M. Zorn, Sean Ekins, Stephen H. Wright and Nathan Cherrington

Drug Metabolism and Disposition May 12, 2021, DMD-AR-2021-000423; DOI: https://doi.org/10.1124/dmd.121.000423
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A new intestinal model for analysis of drug absorption and interactions considering physiological translocation of contents
Satoshi Asano, Aoi Yoshitomo, Shizuka Hozuki, Hiromi Sato, Yasuhiro Kazuki and Akihiro Hisaka

Drug Metabolism and Disposition May 7, 2021, DMD-AR-2021-000361; DOI: https://doi.org/10.1124/dmd.121.000361
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Improving the Translation of Organic Anion Transporting Polypeptide Substrates using HEK293 Cell Data in the Presence and Absence of Human Plasma via PBPK Modeling
Christine M. Bowman, Buyun Chen, Jonathan Cheong, Liling Liu, Yuan Chen and Jialin Mao

Drug Metabolism and Disposition May 6, 2021, DMD-AR-2020-000315; DOI: https://doi.org/10.1124/dmd.120.000315
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Comparative proteomics analysis of the post-mitochondrial supernatant fraction of human lens-free whole eye and liver
Ankit Balhara, Abdul Basit, Upendra A. Argikar, Jennifer L. Dumouchel, Saranjit Singh and Bhagwat Prasad

Drug Metabolism and Disposition May 5, 2021, DMD-AR-2020-000297; DOI: https://doi.org/10.1124/dmd.120.000297
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Evaluation of the Absorption, Metabolism, and Excretion of a Single Oral 1 mg Dose of Tropifexor in Healthy Male Subjects and the Concentration Dependency of Tropifexor Metabolism
Lydia Wang-Lakshman, Zhuang Miao, Lai Wang, Helen Gu, Mark Kagan, Jessie Gu, Elizabeth McNamara, Markus Walles, Ralph Woessner, Gian Camenisch, Heidi J. Einolf and Jin Chen

Drug Metabolism and Disposition May 5, 2021, DMD-AR-2020-000349; DOI: https://doi.org/10.1124/dmd.120.000349

About Drug Metabolism & Disposition

DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

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