Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart

Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn

Special Section of Bile Acids, Drug Metabolism, and Toxicity - freely accessible through October 31, 2022

Special Section on Drug Metabolism in Liver injury and Regeneration - freely accessible through December 31, 2022

  • Aditya Kumar
  • THC/11-OH-THC PBPK in Nonpregnant and Pregnant Women
  • Intestinal Model Considers Physiological Drug Translocation
  • Clearance Predictions Using Human Hepatocyte Spheroids
  • Nonclinical PK and ADME of Givosiran
  • 1
  • 2
  • 3
  • 4
  • 5

Latest Fast Forward Articles

  • You have access
    High-throughput Production of Diverse Xenobiotic Metabolites with P450-Transduced Huh7 Hepatoma Cell Lines
    Choon-myung Lee, Ken H Liu, Grant Singer, Gary W Miller, Shuzhao Li, Dean P Jones and Eddie T. Morgan
    Drug Metabolism and Disposition June 25, 2022, DMD-AR-2022-000900; DOI: https://doi.org/10.1124/dmd.122.000900
  • You have access
    HepaRG cells adopt zonal-like drug-metabolizing phenotypes under physiologically relevant oxygen tensions and Wnt/β-catenin signaling
    Thomas J DiProspero, Lauren G Brown, Trevor D Fachko and Matthew R. Lockett
    Drug Metabolism and Disposition June 14, 2022, DMD-AR-2022-000870; DOI: https://doi.org/10.1124/dmd.122.000870
  • You have access
    The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Abrocitinib, a Selective Janus Kinase Inhibitor, in Humans
    Jonathan N. Bauman, Angela C. Doran, Amanda King-Ahmad, Raman Sharma, Gregory S. Walker, Jian Lin, Tsung H Lin, Jean-Baptiste Telliez, Sakambari Tripathy, Theunis C. Goosen, Christopher Banfield, Bimal K Malhotra and Martin E Dowty
    Drug Metabolism and Disposition June 14, 2022, DMD-AR-2022-000829; DOI: https://doi.org/10.1124/dmd.122.000829
  • You have access
    Cytochrome P450 2J (CYP2J) Genes in Dogs, Cats, and Pigs Are Expressed and Encode Functional Drug-Metabolizing Enzymes
    Yasuhiro Uno, Norie Murayama, Moe Ijiri, Hiroaki Kawaguchi, Osamu Yamato, Mitsuya Shiraishi, Atsushi Asano, Hiroki Teraoka, Hazuki Mizukawa, Shouta M.M. Nakayama, Yoshinori Ikenaka, Mayumi Ishizuka and Hiroshi Yamazaki
    Drug Metabolism and Disposition June 14, 2022, DMD-AR-2022-000930; DOI: https://doi.org/10.1124/dmd.122.000930
  • You have access
    In vitro CYP450 enzyme down-regulation by GLP-1/glucagon co-agonist does not translate to observed drug-drug interactions in the clinic
    Carolina Säll, Lene Alifrangis, Kirsten Dahl, Martin Haljeta Friedrichsen, Sune Boris Nygård and Kim Kristensen
    Drug Metabolism and Disposition June 9, 2022, DMD-AR-2022-000865; DOI: https://doi.org/10.1124/dmd.122.000865
  • You have access
    Characterization of JNJ-2482272 [4-(4-methyl-2-(4-(trifluoromethyl)phenyl)thiazole-5-yl)pyrimidine-2-amine] as a Strong AhR Activator in Rat and Human
    Kevin J. Coe, Mark Feinstein, J. William Higgins, Perry Leung, Brian P Scott, Judith Skaptason, Yuen Tam, Laurie P Volak, Jennifer Kinong, Anton Bittner, Heather McAllister, Nathan M Lim, Michael Hack and Tatiana Koudriakova
    Drug Metabolism and Disposition June 9, 2022, DMD-AR-2021-000825; DOI: https://doi.org/10.1124/dmd.121.000825
View more published ahead of print articles

About Drug Metabolism & Disposition

DMD presents important research in pharmacology and toxicology and is a valuable resource in drug design, drug metabolism, drug transport, expression of drug metabolizing enzymes and transporters, and regulation of drug metabolizing enzyme and transporter gene expression.

Current issue

Drug Metabolism and Disposition: 50 (6)
Drug Metabolism and Disposition
Vol. 50, Issue 6
1 Jun 2022
  • Table of Contents
  • About the Cover
  • Index by author

DMD is published continuously. Articles are added as they are ready and assigned to monthly issues. Check this site for new content or sign up for content alerts.

EDITOR'S CHOICE ARTICLES FOR JUNE 2022:

  • Label-Free but Still Constrained: Assessment of Global Proteomic Strategies for the Quantification of Hepatic Enzymes and Transporters
  • The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human - freely accessible minireview
  • Most Read
Loading
  • Cannabinoid Metabolites as CYP450 Inhibitors
  • Physiology of the Neonatal Gastrointestinal System
  • Pharmacokinetics and Disposition of Biologics
  • Switch from CAR to PXR in the Presence of EGF
  • Alternative P450 Splicing Redirects Human Drug Metabolism
More...
Advertisement
For an alternate route to this Journal use this URL: http://intl-dmd.aspetjournals.org
Back to top
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2022 by the American Society for Pharmacology and Experimental Therapeutics