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Drug Metabolism & Disposition

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Most cited article(s)

  • You have access
    Glucuronidation of Amine Substrates by Purified and Expressed UDP-Glucuronosyltransferase Proteins
    Mitchell D. Green and Thomas R. Tephly
    Drug Metabolism and Disposition September 1998, 26 (9) 860-867;
  • You have access
    Inhibition of Cytochrome P-450 3A (CYP3A) in Human Intestinal and Liver Microsomes: Comparison of K i Values and Impact of CYP3A5 Expression
    Megan A. Gibbs, Kenneth E. Thummel, Danny D. Shen and Kent L. Kunze
    Drug Metabolism and Disposition February 1999, 27 (2) 180-187;
  • You have access
    COMPARISON OF INHIBITORY EFFECTS OF THE PROTON PUMP-INHIBITING DRUGS OMEPRAZOLE, ESOMEPRAZOLE, LANSOPRAZOLE, PANTOPRAZOLE, AND RABEPRAZOLE ON HUMAN CYTOCHROME P450 ACTIVITIES
    Xue-Qing Li, Tommy B. Andersson, Marie Ahlström and Lars Weidolf
    Drug Metabolism and Disposition August 2004, 32 (8) 821-827; DOI: https://doi.org/10.1124/dmd.32.8.821
  • You have access
    HIGH ABSORPTION BUT VERY LOW BIOAVAILABILITY OF ORAL RESVERATROL IN HUMANS
    Thomas Walle, Faye Hsieh, Mark H. DeLegge, John E. Oatis and U. Kristina Walle
    Drug Metabolism and Disposition December 2004, 32 (12) 1377-1382; DOI: https://doi.org/10.1124/dmd.104.000885
  • You have access
    Prediction of Drug Clearance by Glucuronidation from in Vitro Data: Use of Combined Cytochrome P450 and UDP-Glucuronosyltransferase Cofactors in Alamethicin-Activated Human Liver Microsomes
    Peter J. Kilford, Rowan Stringer, Bindi Sohal, J. Brian Houston and Aleksandra Galetin
    Drug Metabolism and Disposition January 2009, 37 (1) 82-89; DOI: https://doi.org/10.1124/dmd.108.023853
  • You have access
    Atypical Kinetic Profiles in Drug Metabolism Reactions
    J. Matthew Hutzler and Timothy S. Tracy
    Drug Metabolism and Disposition April 2002, 30 (4) 355-362; DOI: https://doi.org/10.1124/dmd.30.4.355
  • You have access
    Expression of UGT1A and UGT2B mRNA in Human Normal Tissues and Various Cell Lines
    Akiko Nakamura, Miki Nakajima, Hiroyuki Yamanaka, Ryoichi Fujiwara and Tsuyoshi Yokoi
    Drug Metabolism and Disposition August 2008, 36 (8) 1461-1464; DOI: https://doi.org/10.1124/dmd.108.021428
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    Cyclosporin A drug interactions. Screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes.
    L Pichard, I Fabre, G Fabre, J Domergue, B Saint Aubert, G Mourad and P Maurel
    Drug Metabolism and Disposition September 1990, 18 (5) 595-606;
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    Comparison of Different Algorithms for Predicting Clinical Drug-Drug Interactions, Based on the Use of CYP3A4 in Vitro Data: Predictions of Compounds as Precipitants of Interaction
    Odette A. Fahmi, Susan Hurst, David Plowchalk, Jack Cook, Feng Guo, Kuresh Youdim, Maurice Dickins, Alex Phipps, Amanda Darekar, Ruth Hyland and R. Scott Obach
    Drug Metabolism and Disposition August 2009, 37 (8) 1658-1666; DOI: https://doi.org/10.1124/dmd.108.026252
  • You have access
    The Conduct of in Vitro Studies to Address Time-Dependent Inhibition of Drug-Metabolizing Enzymes: A Perspective of the Pharmaceutical Research and Manufacturers of America
    Scott W. Grimm, Heidi J. Einolf, Steven D. Hall, Kan He, Heng-Keang Lim, Kah-Hiing John Ling, Chuang Lu, Amin A. Nomeir, Eleanore Seibert, Konstantine W. Skordos, George R. Tonn, Robert Van Horn, Regina W. Wang, Y. Nancy Wong, Tian J. Yang and R. Scott Obach
    Drug Metabolism and Disposition July 2009, 37 (7) 1355-1370; DOI: https://doi.org/10.1124/dmd.109.026716

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