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Epidermal Growth Factor Represses Constitutive Androstane Receptor Expression in Primary Human Hepatocytes and Favors Regulation by Pregnane X Receptor
Hugues de Boussac, Claire Gondeau, Philippe Briolotti, Cédric Duret, Fridolin Treindl, Michael Römer, Jean-Michel Fabre, Astrid Herrero, Jeanne Ramos, Patrick Maurel, Markus Templin, Sabine Gerbal-Chaloin and Martine Daujat-Chavanieu

Drug Metabolism and Disposition March 2018, 46 (3) 223-236; DOI: https://doi.org/10.1124/dmd.117.078683
Open Access
Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications
April Neal-Kluever, Jeffrey Fisher, Lawrence Grylack, Satoko Kakiuchi-Kiyota and Wendy Halpern

Drug Metabolism and Disposition March 2019, 47 (3) 296-313; DOI: https://doi.org/10.1124/dmd.118.084418
Open Access
Mechanisms Influencing the Pharmacokinetics and Disposition of Monoclonal Antibodies and Peptides
Amita Datta-Mannan

Drug Metabolism and Disposition October 2019, 47 (10) 1100-1110; DOI: https://doi.org/10.1124/dmd.119.086488
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Finding T_max and C_max in Multicompartmental Models
Yi Rang Han, Ping I. Lee and K. Sandy Pang

Drug Metabolism and Disposition November 2018, 46 (11) 1796-1804; DOI: https://doi.org/10.1124/dmd.118.082636
Open Access
Primary Human Hepatocyte Spheroids as an In Vitro Tool for Investigating Drug Compounds with Low Hepatic Clearance
Julia Riede, Birgit M. Wollmann, Espen Molden and Magnus Ingelman-Sundberg

Drug Metabolism and Disposition July 2021, 49 (7) 501-508; DOI: https://doi.org/10.1124/dmd.120.000340
Open Access
Comparative Hepatic and Intestinal Efflux Transport of Statins
Feng Deng, Suvi-Kukka Tuomi, Mikko Neuvonen, Päivi Hirvensalo, Sami Kulju, Christoph Wenzel, Stefan Oswald, Anne M. Filppula and Mikko Niemi

Drug Metabolism and Disposition September 2021, 49 (9) 750-759; DOI: https://doi.org/10.1124/dmd.121.000430
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Successful Prediction of Human Fetal Exposure to P-Glycoprotein Substrate Drugs Using the Proteomics-Informed Relative Expression Factor Approach and PBPK Modeling and Simulation
Olena Anoshchenko, Flavia Storelli and Jashvant D. Unadkat

Drug Metabolism and Disposition October 2021, 49 (10) 919-928; DOI: https://doi.org/10.1124/dmd.121.000538
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Pharmacokinetic Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration in 2020: Mechanistic Understanding and Clinical Recommendations
Jingjing Yu, Yan Wang and Isabelle Ragueneau-Majlessi

Drug Metabolism and Disposition October 7, 2021, DMD-MR-2021-000401; DOI: https://doi.org/10.1124/dmd.121.000401
Open Access
Evaluation of Normothermic Machine Perfusion of Porcine Livers as a Novel Preclinical Model to Predict Biliary Clearance and Transporter-Mediated Drug-Drug Interactions Using Statins
L. J. Stevens, A. Z. X. Zhu, P. P. Chothe, S. K. Chowdhury, J. M. Donkers, W. H. J. Vaes, C. A. J. Knibbe, I. P. J. Alwayn and E. van de Steeg

Drug Metabolism and Disposition September 2021, 49 (9) 780-789; DOI: https://doi.org/10.1124/dmd.121.000521
Open Access
Identification of Human UDP-Glucuronosyltransferase and Sulfotransferase as Responsible for the Metabolism of Dotinurad, a Novel Selective Urate Reabsorption Inhibitor
Koichi Omura, Keisuke Motoki, Seiichi Kobashi, Kengo Miyata, Katsuhiro Yamano and Takashi Iwanaga

Drug Metabolism and Disposition November 2021, 49 (11) 1016-1024; DOI: https://doi.org/10.1124/dmd.120.000251

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