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Mechanisms Influencing the Pharmacokinetics and Disposition of Monoclonal Antibodies and Peptides
Amita Datta-Mannan

Drug Metabolism and Disposition October 2019, 47 (10) 1100-1110; DOI: https://doi.org/10.1124/dmd.119.086488
Open Access
Physiology of the Neonatal Gastrointestinal System Relevant to the Disposition of Orally Administered Medications
April Neal-Kluever, Jeffrey Fisher, Lawrence Grylack, Satoko Kakiuchi-Kiyota and Wendy Halpern

Drug Metabolism and Disposition March 2019, 47 (3) 296-313; DOI: https://doi.org/10.1124/dmd.118.084418
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Absorption, Metabolism, and Excretion, In Vitro Pharmacology, and Clinical Pharmacokinetics of Ozanimod, a Novel Sphingosine 1-Phosphate Receptor Modulator
Sekhar Surapaneni, Usha Yerramilli, April Bai, Deepak Dalvie, Jennifer Brooks, Xiaomin Wang, Julie V. Selkirk, Yingzhuo Grace Yan, Peijin Zhang, Richard Hargreaves, Gondi Kumar, Maria Palmisano and Jonathan Q. Tran

Drug Metabolism and Disposition May 2021, 49 (5) 405-419; DOI: https://doi.org/10.1124/dmd.120.000220
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Drug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic Modalities
Donglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus Khojasteh

Drug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
Open Access
Metabolism and Disposition of Volanesorsen, a 2′-O-(2 methoxyethyl) Antisense Oligonucleotide, Across Species
Noah Post, Rosie Yu, Sarah Greenlee, Hans Gaus, Eunju Hurh, John Matson and Yanfeng Wang

Drug Metabolism and Disposition October 2019, 47 (10) 1164-1173; DOI: https://doi.org/10.1124/dmd.119.087395
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Insights into the Authentic Active Ingredients and Action Sites of Oral Exogenous Glutathione in the Treatment of Ischemic Brain Injury Based on Pharmacokinetic-Pharmacodynamic Studies
Chong Chen, Qingqing Ding, Boyu Shen, Tengjie Yu, He Wang, Yangfan Xu, Huimin Guo, Kangrui Hu, Lin Xie, Guangji Wang and Yan Liang

Drug Metabolism and Disposition January 2020, 48 (1) 52-62; DOI: https://doi.org/10.1124/dmd.119.089458
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In Vivo Functional Effects of CYP2C9 M1L, a Novel and Common Variant in the Yup’ik Alaska Native Population
Lindsay M. Henderson, Scarlett E. Hopkins, Bert B. Boyer, Timothy A. Thornton, Allan E. Rettie and Kenneth E. Thummel

Drug Metabolism and Disposition May 2021, 49 (5) 345-352; DOI: https://doi.org/10.1124/dmd.120.000301
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Cytochrome P450 3A Time-Dependent Inhibition Assays are Too Sensitive for Identification of Drugs Causing Clinically Significant Drug-Drug Interactions: A Comparison of Human Liver Microsomes and Hepatocytes and Definition of Boundaries for Inactivation Rate Constants
Heather Eng, Elaine Tseng, Matthew A. Cerny, Theunis C. Goosen and R. Scott Obach

Drug Metabolism and Disposition April 2, 2021, DMD-AR-2021-000356; DOI: https://doi.org/10.1124/dmd.121.000356
Open Access
Revisiting Nonlinear Bosentan Pharmacokinetics by Physiologically Based Pharmacokinetic Modeling: Target Binding, Albeit Not a Major Contributor to Nonlinearity, Can Offer Prediction of Target Occupancy
Satoshi Koyama, Kota Toshimoto, Wooin Lee, Yasunori Aoki and Yuichi Sugiyama

Drug Metabolism and Disposition April 2021, 49 (4) 298-304; DOI: https://doi.org/10.1124/dmd.120.000023
Open Access
Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs
Philip Gardiner, Rhona J. Cox and Ken Grime

Drug Metabolism and Disposition August 2019, 47 (8) 865-873; DOI: https://doi.org/10.1124/dmd.119.087163

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