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Clinical Investigation of Metabolic and Renal Clearance Pathways Contributing to the Elimination of Fevipiprant Using Probenecid as Perpetrator
H. Markus Weiss, Thomas Langenickel, Meredith Cain, Swarupa Kulkarni, Bharti Shah, Janardhana Vemula, Gholamreza Rahmanzadeh and Birk Poller

Drug Metabolism and Disposition May 2021, 49 (5) 389-394; DOI: https://doi.org/10.1124/dmd.120.000273
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SLCO1B1: Application and Limitations of Deep Mutational Scanning for Genomic Missense Variant Function
Lingxin Zhang, Vivekananda Sarangi, Ming-Fen Ho, Irene Moon, Krishna R. Kalari, Liewei Wang and Richard M. Weinshilboum

Drug Metabolism and Disposition May 2021, 49 (5) 395-404; DOI: https://doi.org/10.1124/dmd.120.000264
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Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification
Jennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina Isoherranen

Drug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920
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Metabolism and Mass Balance of the Novel Nonsteroidal Androgen Receptor Inhibitor Darolutamide in Humans
Päivi Taavitsainen, Olaf Prien, Marja Kähkönen, Michael Niehues, Timo Korjamo, Karsten Denner, Pirjo Nykänen, Annamari Vuorela, Natalia A. Jungmann, Clemens-Jeremias von Bühler, Mikko Koskinen, Christian Zurth and Hille Gieschen

Drug Metabolism and Disposition June 2021, 49 (6) 420-433; DOI: https://doi.org/10.1124/dmd.120.000309
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Pharmacokinetic and biochemical profiling of Sodium Dichloroacetate in pregnant ewes and fetuses
Serene Joseph, Abhisheak Sharma, Lloyd P. Horne, Charles E. Wood, Taimour Langaee, Margaret O. James, Peter W. Stacpoole and Maureen Keller-Wood

Drug Metabolism and Disposition April 2, 2021, DMD-AR-2020-000330; DOI: https://doi.org/10.1124/dmd.120.000330
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The Reliability of Estimating K_i Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC₅₀ Values: A Retrospective Analysis of 343 Experiments
Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson

Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
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IVIVE of Transporter-Mediated Renal Clearance: Relative Expression Factor (REF) vs Relative Activity Factor (RAF) Approach
Aditya R. Kumar, Bhagwat Prasad, Deepak Kumar Bhatt, Sumathy Mathialagan, Manthena V. S. Varma and Jashvant D. Unadkat

Drug Metabolism and Disposition April 6, 2021, DMD-AR-2021-000367; DOI: https://doi.org/10.1124/dmd.121.000367
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Microbiome Disturbances and Autism Spectrum Disorders
Cheryl S. Rosenfeld

Drug Metabolism and Disposition October 2015, 43 (10) 1557-1571; DOI: https://doi.org/10.1124/dmd.115.063826
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Use of Hybrid Capillary Tube Apparatus on 400 MHz NMR for Quantitation of Crucial Low-Quantity Metabolites Using aSICCO Signal
Ranjeet Tiwari, Deepak Ahire, Hemantha Kumar, Sarmistha Sinha, Siddheshwar Kisan Chauthe, Murali Subramanian, Ramaswamy Iyer, Ramakanth Sarabu and Lakshmikant Bajpai

Drug Metabolism and Disposition December 2017, 45 (12) 1215-1224; DOI: https://doi.org/10.1124/dmd.117.077073
Open Access
Prediction of Transporter-Mediated Drug-Drug Interactions and Phenotyping of Hepatobiliary Transporters Involved in the Clearance of E7766, a Novel Macrocycle-Bridged Dinucleotide
Rongrong Jiang, Andrew Hart, Laurette Burgess, Dae-Shik Kim, Weidong George Lai and Vaishali Dixit

Drug Metabolism and Disposition March 2021, 49 (3) 265-275; DOI: https://doi.org/10.1124/dmd.120.000125

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