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Evaluation of the disconnect between hepatocyte and microsome intrinsic clearance and in vitro in vivo extrapolation performance.
Beth Williamson, Stephanie Harlfinger and Dermot F McGinnity

Drug Metabolism and Disposition August 26, 2020, DMD-AR-2020-000131; DOI: https://doi.org/10.1124/dmd.120.000131
Open Access
Abemaciclib Does Not Have a Clinically Meaningful Effect on Pharmacokinetics of CYP1A2, CYP2C9, CYP2D6, and CYP3A4 Substrates in Patients with Cancer
P. Kellie Turner, Stephen D. Hall, Sonya C. Chapman, Jessica L. Rehmel, Jane E. Royalty, Yingying Guo and Palaniappan Kulanthaivel

Drug Metabolism and Disposition September 2020, 48 (9) 796-803; DOI: https://doi.org/10.1124/dmd.119.090092
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Pharmacokinetic Modeling of the Subcutaneous Absorption of Therapeutic Proteins
Leonid Kagan

Drug Metabolism and Disposition November 2014, 42 (11) 1890-1905; DOI: https://doi.org/10.1124/dmd.114.059121
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The Reliability of Estimating K_i Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC₅₀ Values: A Retrospective Analysis of 343 Experiments
Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson

Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
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New Author Guidelines for Displaying Data and Reporting Data Analysis and Statistical Methods in Experimental Biology
Martin C. Michel, T.J. Murphy and Harvey J. Motulsky

Drug Metabolism and Disposition January 2020, 48 (1) 64-74; DOI: https://doi.org/10.1124/dmd.119.090027
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The MBNL/CELF Splicing Factors Regulate Cytosolic Sulfotransferase 4A1 Protein Expression during Cell Differentiation
Misgana Idris, Neville J. Butcher and Rodney F. Minchin

Drug Metabolism and Disposition March 2019, 47 (3) 314-319; DOI: https://doi.org/10.1124/dmd.118.085290
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Microbiome Disturbances and Autism Spectrum Disorders
Cheryl S. Rosenfeld

Drug Metabolism and Disposition October 2015, 43 (10) 1557-1571; DOI: https://doi.org/10.1124/dmd.115.063826
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A Decade in the MIST: Learnings from Investigations of Drug Metabolites in Drug Development under the “Metabolites in Safety Testing” Regulatory Guidance
Simone Schadt, Bojan Bister, Swapan K. Chowdhury, Christoph Funk, Cornelis E. C. A. Hop, W. Griffith Humphreys, Fumihiko Igarashi, Alexander D. James, Mark Kagan, S. Cyrus Khojasteh, Angus N. R. Nedderman, Chandra Prakash, Frank Runge, Holger Scheible, Douglas K. Spracklin, Piet Swart, Susanna Tse, Josh Yuan and R. Scott Obach

Drug Metabolism and Disposition June 2018, 46 (6) 865-878; DOI: https://doi.org/10.1124/dmd.117.079848
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Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland

Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350
Open Access
Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs
Philip Gardiner, Rhona J. Cox and Ken Grime

Drug Metabolism and Disposition August 2019, 47 (8) 865-873; DOI: https://doi.org/10.1124/dmd.119.087163

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