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Effect of Human Plasma on Hepatic Uptake of Organic Anion–Transporting Polypeptide 1B Substrates: Studies Using Transfected Cells and Primary Human Hepatocytes
Yi-an Bi, Sangwoo Ryu, David A. Tess, A. David Rodrigues and Manthena V. S. Varma

Drug Metabolism and Disposition January 2021, 49 (1) 72-83; DOI: https://doi.org/10.1124/dmd.120.000134
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Microbiome Disturbances and Autism Spectrum Disorders
Cheryl S. Rosenfeld

Drug Metabolism and Disposition October 2015, 43 (10) 1557-1571; DOI: https://doi.org/10.1124/dmd.115.063826
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Functional Characterization of 40 CYP3A4 Variants by Assessing Midazolam 1′-Hydroxylation and Testosterone 6β-Hydroxylation
Masaki Kumondai, Evelyn Marie Gutiérrez Rico, Eiji Hishinuma, Akiko Ueda, Sakae Saito, Daisuke Saigusa, Shu Tadaka, Kengo Kinoshita, Tomoki Nakayoshi, Akifumi Oda, Ai Abe, Masamitsu Maekawa, Nariyasu Mano, Noriyasu Hirasawa and Masahiro Hiratsuka

Drug Metabolism and Disposition March 2021, 49 (3) 212-220; DOI: https://doi.org/10.1124/dmd.120.000261
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In Vivo Gene Expression Profile of Human Intestinal Epithelial Cells: From the Viewpoint of Drug Metabolism and Pharmacokinetics
Kazuo Takayama, Kohei Ito, Akiko Matsui, Tomoki Yamashita, Kentaro Kawakami, Daisuke Hirayama, Wataru Kishimoto, Hiroshi Nakase and Hiroyuki Mizuguchi

Drug Metabolism and Disposition March 2021, 49 (3) 221-232; DOI: https://doi.org/10.1124/dmd.120.000283
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Optimization of Canalicular ABC Transporter Function in HuH-7 Cells by Modification of Culture Conditions
Hee Eun Kang, Melina M. Malinen, Chitra Saran, Paavo Honkakoski and Kim L.R. Brouwer

Drug Metabolism and Disposition October 2019, 47 (10) 1222-1230; DOI: https://doi.org/10.1124/dmd.119.087676
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The Reliability of Estimating K_i Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC₅₀ Values: A Retrospective Analysis of 343 Experiments
Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson

Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
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Significance of Multiple Bioactivation Pathways for Meclofenamate as Revealed through Modeling and Reaction Kinetics
Mary Alexandra Schleiff, Noah R. Flynn, Sasin Payakachat, Benjamin Mark Schleiff, Anna O. Pinson, Dennis W. Province, S. Joshua Swamidass, Gunnar Boysen and Grover P. Miller

Drug Metabolism and Disposition February 2021, 49 (2) 133-141; DOI: https://doi.org/10.1124/dmd.120.000254
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Interaction and Transport of Methamphetamine and its Primary Metabolites by Organic Cation and Multidrug and Toxin Extrusion Transporters
David J. Wagner, Jennifer E. Sager, Haichuan Duan, Nina Isoherranen and Joanne Wang

Drug Metabolism and Disposition July 2017, 45 (7) 770-778; DOI: https://doi.org/10.1124/dmd.116.074708
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Finding T_max and C_max in Multicompartmental Models
Yi Rang Han, Ping I. Lee and K. Sandy Pang

Drug Metabolism and Disposition November 2018, 46 (11) 1796-1804; DOI: https://doi.org/10.1124/dmd.118.082636
Open Access
Plasma Protein Binding as an Optimizable Parameter for Acidic Drugs
Philip Gardiner, Rhona J. Cox and Ken Grime

Drug Metabolism and Disposition August 2019, 47 (8) 865-873; DOI: https://doi.org/10.1124/dmd.119.087163

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