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Tetrahydrocannabinol and Its Major Metabolites Are Not (or Are Poor) Substrates or Inhibitors of Human P-Glycoprotein [ATP-Binding Cassette (ABC) B1] and Breast Cancer Resistance Protein (ABCG2)
Xin Chen, Jashvant D. Unadkat and Qingcheng Mao

Drug Metabolism and Disposition October 2021, 49 (10) 910-918; DOI: https://doi.org/10.1124/dmd.121.000505
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Quantitation of Plasma Membrane Drug Transporters in Kidney Tissue and Cell Lines Using a Novel Proteomic Approach Enabled a Prospective Prediction of Metformin Disposition
Ryota Kikuchi, William J. Chiou, Kenneth R. Durbin, John P. Savaryn, Junli Ma, Arian Emami Riedmaier, Sonia M. de Morais, Gary J. Jenkins and Daniel A.J. Bow

Drug Metabolism and Disposition October 2021, 49 (10) 938-946; DOI: https://doi.org/10.1124/dmd.121.000487
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Cytochrome b₅ Binds Tightly to Several Human Cytochrome P450 Enzymes
Donghak Kim, Vitchan Kim, Yasuhiro Tateishi and F. Peter Guengerich

Drug Metabolism and Disposition October 2021, 49 (10) 902-909; DOI: https://doi.org/10.1124/dmd.121.000475
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Icotinib Induces Mechanism-Based Inactivation of Recombinant Human CYP3A4/5 Possibly via Heme Destruction by Ketene Intermediate
Chen Sun, Huimin Zhao, Wei Li, Yudi Jia, Yi Yang, Ying Peng and Jiang Zheng

Drug Metabolism and Disposition October 2021, 49 (10) 892-901; DOI: https://doi.org/10.1124/dmd.121.000369
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Finding T_max and C_max in Multicompartmental Models
Yi Rang Han, Ping I. Lee and K. Sandy Pang

Drug Metabolism and Disposition November 2018, 46 (11) 1796-1804; DOI: https://doi.org/10.1124/dmd.118.082636
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The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
Robin McDougall, Diane Ramsden, Sagar Agarwal, Saket Agarwal, Krishna Aluri, Michael Arciprete, Christopher Brown, Elena Castellanos-Rizaldos, Klaus Charisse, Saeho Chong, Joseph Cichocki, Kevin Fitzgerald, Varun Goel, Yongli Gu, Dale Guenther, Bahru Habtemariam, Vasant Jadhav, Maja Janas, Muthusamy Jayaraman, Jeffrey Kurz, Jing Li, Ju Liu, Xiumin Liu, Steven Liou, Chris Maclauchlin, Martin Maier, Muthiah Manoharan, Jayaprakash K. Nair, Gabriel Robbie, Karyn Schmidt, Peter Smith, Christopher Theile, Akshay Vaishnaw, Scott Waldron, Yuanxin Xu, Xuemei Zhang, Ivan Zlatev and Jing-Tao Wu

Drug Metabolism and Disposition June 2022, 50 (6) 781-797; DOI: https://doi.org/10.1124/dmd.121.000428
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Disposition of Nirmatrelvir, an Orally Bioavailable Inhibitor of SARS-CoV-2 3C-Like Protease, across Animals and Humans
Heather Eng, Alyssa L. Dantonio, Eugene P. Kadar, R. Scott Obach, Li Di, Jian Lin, Nandini C. Patel, Britton Boras, Gregory S. Walker, Jonathan J. Novak, Emi Kimoto, Ravi Shankar P. Singh and Amit S. Kalgutkar

Drug Metabolism and Disposition May 2022, 50 (5) 576-590; DOI: https://doi.org/10.1124/dmd.121.000801
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Determination of Acyl-, O-, and N-Glucuronide Using Chemical Derivatization Coupled with Liquid Chromatography–High-Resolution Mass Spectrometry
Yukuang Guo, Abhi Shah, Eugene Oh, Swapan K. Chowdhury and Xiaochun Zhu

Drug Metabolism and Disposition May 2022, 50 (5) 716-724; DOI: https://doi.org/10.1124/dmd.122.000832
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Interaction and Transport of Methamphetamine and its Primary Metabolites by Organic Cation and Multidrug and Toxin Extrusion Transporters
David J. Wagner, Jennifer E. Sager, Haichuan Duan, Nina Isoherranen and Joanne Wang

Drug Metabolism and Disposition July 2017, 45 (7) 770-778; DOI: https://doi.org/10.1124/dmd.116.074708
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Pharmacokinetic and Drug Metabolism Properties of Novel Therapeutic Modalities
Brooke M. Rock and Robert S. Foti

Drug Metabolism and Disposition October 2019, 47 (10) 1097-1099; DOI: https://doi.org/10.1124/dmd.119.088708

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