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Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di

Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
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Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification
Jennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina Isoherranen

Drug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920
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Seeking Nonspecific Binding: Assessing the Reliability of Tissue Dilutions for Calculating Fraction Unbound
William J. Jusko, Emilie A.G. Molins and Vivaswath S. Ayyar

Drug Metabolism and Disposition October 2020, 48 (10) 894-902; DOI: https://doi.org/10.1124/dmd.120.000118
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The Drug-Drug Interaction Potential of Antiviral Agents for the Treatment of Chronic Hepatitis C Infection
Kimberly L. Garrison, Polina German, Erik Mogalian and Anita Mathias

Drug Metabolism and Disposition August 2018, 46 (8) 1212-1225; DOI: https://doi.org/10.1124/dmd.117.079038
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Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and Disease
Diede Fennema, Ian R. Phillips and Elizabeth A. Shephard

Drug Metabolism and Disposition November 2016, 44 (11) 1839-1850; DOI: https://doi.org/10.1124/dmd.116.070615
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Brain Exposure of Two Selective Dual CDK4 and CDK6 Inhibitors and the Antitumor Activity of CDK4 and CDK6 Inhibition in Combination with Temozolomide in an Intracranial Glioblastoma Xenograft
Thomas J. Raub, Graham N. Wishart, Palaniappan Kulanthaivel, Brian A. Staton, Rose T. Ajamie, Geri A. Sawada, Lawrence M. Gelbert, Harlan E. Shannon, Concepcion Sanchez-Martinez and Alfonso De Dios

Drug Metabolism and Disposition September 2015, 43 (9) 1360-1371; DOI: https://doi.org/10.1124/dmd.114.062745
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Mechanisms of Herb-Drug Interactions Involving Cinnamon and Cytochrome P450 2A6: Focus on Time-dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde
Michael J. Espiritu, Justin Chen, Jaydeep Yadav, Michael Larkin, Robert D. Pelletier, Jeannine M. Chan, Jeevan B. GC, Senthil Natesan and John P. Harrelson

Drug Metabolism and Disposition August 12, 2020, DMD-AR-2020-000087; DOI: https://doi.org/10.1124/dmd.120.000087
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Physiologically Based Pharmacokinetic Modeling for Sequential Metabolism: Effect of CYP2C19 Genetic Polymorphism on Clopidogrel and Clopidogrel Active Metabolite Pharmacokinetics
Nassim Djebli, David Fabre, Xavier Boulenc, Gérard Fabre, Eric Sultan and Fabrice Hurbin

Drug Metabolism and Disposition April 2015, 43 (4) 510-522; DOI: https://doi.org/10.1124/dmd.114.062596
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Glycyrrhizin Alleviates Nonalcoholic Steatohepatitis via Modulating Bile Acids and Meta-Inflammation
Tingting Yan, Hong Wang, Lijuan Cao, Qiong Wang, Shogo Takahashi, Tomoki Yagai, Guolin Li, Kristopher W. Krausz, Guangji Wang, Frank J. Gonzalez and Haiping Hao

Drug Metabolism and Disposition September 2018, 46 (9) 1310-1319; DOI: https://doi.org/10.1124/dmd.118.082008
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Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation
Yuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. Patterson

Drug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691

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