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The Complexities of Interpreting Reversible Elevated Serum Creatinine Levels in Drug Development: Does a Correlation with Inhibition of Renal Transporters Exist?
Xiaoyan Chu, Kelly Bleasby, Grace Hoyee Chan, Irene Nunes and Raymond Evers

Drug Metabolism and Disposition September 2016, 44 (9) 1498-1509; DOI: https://doi.org/10.1124/dmd.115.067694
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Drug Concentration Asymmetry in Tissues and Plasma for Small Molecule–Related Therapeutic Modalities
Donglu Zhang, Cornelis E.C.A. Hop, Gabriela Patilea-Vrana, Gautham Gampa, Herana Kamal Seneviratne, Jashvant D. Unadkat, Jane R. Kenny, Karthik Nagapudi, Li Di, Lian Zhou, Mark Zak, Matthew R. Wright, Namandjé N. Bumpus, Richard Zang, Xingrong Liu, Yurong Lai and S. Cyrus Khojasteh

Drug Metabolism and Disposition October 2019, 47 (10) 1122-1135; DOI: https://doi.org/10.1124/dmd.119.086744
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Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements
Alyssa A. Sprouse and Richard B. van Breemen

Drug Metabolism and Disposition February 2016, 44 (2) 162-171; DOI: https://doi.org/10.1124/dmd.115.066902
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Porcine Prediction of Pharmacokinetic Parameters in People: A Pig in a Poke?
Huadong Tang and Michael Mayersohn

Drug Metabolism and Disposition November 2018, 46 (11) 1712-1724; DOI: https://doi.org/10.1124/dmd.118.083311
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Cytochrome P450 and Non–Cytochrome P450 Oxidative Metabolism: Contributions to the Pharmacokinetics, Safety, and Efficacy of Xenobiotics
Robert S. Foti and Deepak K. Dalvie

Drug Metabolism and Disposition August 2016, 44 (8) 1229-1245; DOI: https://doi.org/10.1124/dmd.116.071753
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Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
Y. Kapelyukh, C. J. Henderson, N. Scheer, A. Rode and C. R. Wolf

Drug Metabolism and Disposition August 2019, 47 (8) 907-918; DOI: https://doi.org/10.1124/dmd.119.087718
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Trend Analysis of a Database of Intravenous Pharmacokinetic Parameters in Humans for 1352 Drug Compounds
Franco Lombardo, Giuliano Berellini and R. Scott Obach

Drug Metabolism and Disposition November 2018, 46 (11) 1466-1477; DOI: https://doi.org/10.1124/dmd.118.082966
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Gut Microbiota-Mediated Drug-Antibiotic Interactions
Dong-Hyun Kim

Drug Metabolism and Disposition October 2015, 43 (10) 1581-1589; DOI: https://doi.org/10.1124/dmd.115.063867
Open Access
Bioavailability, Biotransformation, and Excretion of the Covalent Bruton Tyrosine Kinase Inhibitor Acalabrutinib in Rats, Dogs, and Humans
Terry Podoll, Paul G. Pearson, Jerry Evarts, Tim Ingallinera, Elena Bibikova, Hao Sun, Mark Gohdes, Kristen Cardinal, Mitesh Sanghvi and J. Greg Slatter

Drug Metabolism and Disposition February 2019, 47 (2) 145-154; DOI: https://doi.org/10.1124/dmd.118.084459
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Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation
Troy D. Hubbard, Iain A. Murray and Gary H. Perdew

Drug Metabolism and Disposition October 2015, 43 (10) 1522-1535; DOI: https://doi.org/10.1124/dmd.115.064246

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