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A Comparison of Total and Plasma Membrane Abundance of Transporters in Suspended, Plated, Sandwich-Cultured Human Hepatocytes Versus Human Liver Tissue Using Quantitative Targeted Proteomics and Cell Surface Biotinylation
Vineet Kumar, Laurent Salphati, Cornelis E. C. A. Hop, Guangqing Xiao, Yurong Lai, Anita Mathias, Xiaoyan Chu, W. Griffith Humphreys, Mingxiang Liao, Scott Heyward and Jashvant D. Unadkat

Drug Metabolism and Disposition April 2019, 47 (4) 350-357; DOI: https://doi.org/10.1124/dmd.118.084988
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Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements
Alyssa A. Sprouse and Richard B. van Breemen

Drug Metabolism and Disposition February 2016, 44 (2) 162-171; DOI: https://doi.org/10.1124/dmd.115.066902
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Mechanisms and Clinical Significance of Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration in 2017
Jingjing Yu, Ichiko D. Petrie, René H. Levy and Isabelle Ragueneau-Majlessi

Drug Metabolism and Disposition February 2019, 47 (2) 135-144; DOI: https://doi.org/10.1124/dmd.118.084905
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Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation
Yuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. Patterson

Drug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
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Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor
Paul A. Dickinson, Mireille V. Cantarini, Jo Collier, Paul Frewer, Scott Martin, Kathryn Pickup and Peter Ballard

Drug Metabolism and Disposition August 2016, 44 (8) 1201-1212; DOI: https://doi.org/10.1124/dmd.115.069203
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Prediction of Human Distribution Volumes of Compounds in Various Elimination Phases Using Physiologically Based Pharmacokinetic Modeling and Experimental Pharmacokinetics in Animals
Hidetoshi Shimizu, Kosuke Yoshida, Tomohisa Nakada, Koki Kojima, Akihito Ogasawara, Yoshinobu Nakamaru and Hiroshi Yamazaki

Drug Metabolism and Disposition February 2019, 47 (2) 114-123; DOI: https://doi.org/10.1124/dmd.118.083642
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Alternative Splicing in the Cytochrome P450 Superfamily Expands Protein Diversity to Augment Gene Function and Redirect Human Drug Metabolism
Andrew J. Annalora, Craig B. Marcus and Patrick L. Iversen

Drug Metabolism and Disposition April 2017, 45 (4) 375-389; DOI: https://doi.org/10.1124/dmd.116.073254
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Effects of Pregnancy on the Pharmacokinetics of Metformin
Michael Z. Liao, Shannon K. Flood Nichols, Mahmoud Ahmed, Shannon Clark, Gary D. Hankins, Steve Caritis, Raman Venkataramanan, David Haas, Sara K. Quinney, Laura S. Haneline, Alan T. Tita, Tracy Manuck, Joanne Wang, Kenneth E. Thummel, Linda Morris Brown, Zhaoxia Ren, Thomas R. Easterling and Mary F. Hebert

Drug Metabolism and Disposition April 2020, 48 (4) 264-271; DOI: https://doi.org/10.1124/dmd.119.088435
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Evaluation of the Disconnect between Hepatocyte and Microsome Intrinsic Clearance and In Vitro In Vivo Extrapolation Performance
Beth Williamson, Stephanie Harlfinger and Dermot F. McGinnity

Drug Metabolism and Disposition November 2020, 48 (11) 1137-1146; DOI: https://doi.org/10.1124/dmd.120.000131
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Calibrating the In Vitro–In Vivo Correlation for OATP-Mediated Drug-Drug Interactions with Rosuvastatin Using Static and PBPK Models
Rucha Sane, Kit Wun Kathy Cheung, Péter Kovács, Taleah Farasyn, Ruina Li, Annamaria Bui, Luna Musib, Emese Kis, Emile Plise and Zsuzsanna Gáborik

Drug Metabolism and Disposition December 2020, 48 (12) 1264-1270; DOI: https://doi.org/10.1124/dmd.120.000149

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