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Drug Metabolism & Disposition

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Most read article(s)

  • Open Access
    Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and Disease
    Diede Fennema, Ian R. Phillips and Elizabeth A. Shephard
    Drug Metabolism and Disposition November 2016, 44 (11) 1839-1850; DOI: https://doi.org/10.1124/dmd.116.070615
  • You have access
    Effect of Gender and Various Diets on Bile Acid Profile and Related Genes in Mice
    Chong Ma, Ying Guo and Curtis D. Klaassen
    Drug Metabolism and Disposition January 2021, 49 (1) 62-71; DOI: https://doi.org/10.1124/dmd.120.000166
  • You have access
    Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation
    Troy D. Hubbard, Iain A. Murray and Gary H. Perdew
    Drug Metabolism and Disposition October 2015, 43 (10) 1522-1535; DOI: https://doi.org/10.1124/dmd.115.064246
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    Berberine Directly Affects the Gut Microbiota to Promote Intestinal Farnesoid X Receptor Activation
    Yuan Tian, Jingwei Cai, Wei Gui, Robert G. Nichols, Imhoi Koo, Jingtao Zhang, Mallappa Anitha and Andrew D. Patterson
    Drug Metabolism and Disposition February 2019, 47 (2) 86-93; DOI: https://doi.org/10.1124/dmd.118.083691
  • Sex-, Age-, and Race/Ethnicity-Dependent Variations in Drug-Processing and NRF2-Regulated Genes in Human Livers
    You have access
    Sex-, Age-, and Race/Ethnicity-Dependent Variations in Drug-Processing and NRF2-Regulated Genes in Human Livers
    Jie Liu, Julia Yue Cui, Yuan-Fu Lu, J. Christopher Corton and Curtis D. Klaassen
    Drug Metabolism and Disposition January 2021, 49 (1) 111-119; DOI: https://doi.org/10.1124/dmd.120.000181
  • You have access
    Function and Expression of Bile Salt Export Pump in Suspension Human Hepatocytes
    Paresh P. Chothe, Rachel Pemberton and Niresh Hariparsad
    Drug Metabolism and Disposition January 20, 2021, DMD-AR-2020-000057; DOI: https://doi.org/10.1124/dmd.120.000057
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    Determination of Human Hepatocyte Intrinsic Clearance for Slowly Metabolized Compounds: Comparison of a Primary Hepatocyte/Stromal Cell Co-culture with Plated Primary Hepatocytes and HepaRG
    Britta Bonn, Petter Svanberg, Annika Janefeldt, Ia Hultman and Ken Grime
    Drug Metabolism and Disposition April 2016, 44 (4) 527-533; DOI: https://doi.org/10.1124/dmd.115.067769
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    In Vitro Metabolism of Slowly Cleared G Protein–Coupled Receptor 139 Agonist TAK-041 Using Rat, Dog, Monkey, and Human Hepatocyte Models (HepatoPac): Correlation with In Vivo Metabolism
    Amin Kamel, Steve Bowlin, Natalie Hosea, Dimitrios Arkilo and Antonio Laurenza
    Drug Metabolism and Disposition February 2021, 49 (2) 121-132; DOI: https://doi.org/10.1124/dmd.120.000246
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    Transporter Expression in Liver Tissue from Subjects with Alcoholic or Hepatitis C Cirrhosis Quantified by Targeted Quantitative Proteomics
    Li Wang, Carol Collins, Edward J. Kelly, Xiaoyan Chu, Adrian S. Ray, Laurent Salphati, Guangqing Xiao, Caroline Lee, Yurong Lai, Mingxiang Liao, Anita Mathias, Raymond Evers, William Humphreys, Cornelis E. C. A. Hop, Sean C. Kumer and Jashvant D. Unadkat
    Drug Metabolism and Disposition November 2016, 44 (11) 1752-1758; DOI: https://doi.org/10.1124/dmd.116.071050
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    Polymorphisms of the Multidrug Pump ABCG2: A Systematic Review of Their Effect on Protein Expression, Function, and Drug Pharmacokinetics
    Niall Heyes, Parth Kapoor and Ian D. Kerr
    Drug Metabolism and Disposition December 2018, 46 (12) 1886-1899; DOI: https://doi.org/10.1124/dmd.118.083030

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