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Drug Metabolism & Disposition

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Table of Contents

November 01, 1983; Volume 11,Issue 6
  • You have access
    Effects of model traumatic injury on hepatic drug metabolism in the rat. I. In vivo antipyrine metabolism.
    L K Griffeth, G M Rosen, C Tschanz and E J Rauckman
    Drug Metabolism and Disposition November 1983, 11 (6) 517-525;
  • You have access
    The relationship between paraquat accumulation and covalent binding in rat lung slices.
    T M Sullivan and M R Montgomery
    Drug Metabolism and Disposition November 1983, 11 (6) 526-530;
  • You have access
    Cytochrome P-450-dependent oxidation of the 17 alpha-ethynyl group of synthetic steroids. D-homoannulation or enzyme inactivation.
    S E Schmid, W Y Au, D E Hill, F F Kadlubar and W Slikker
    Drug Metabolism and Disposition November 1983, 11 (6) 531-536;
  • You have access
    Disposition of 4,4'-thiobis(6-t-butyl-m-cresol) in rats.
    L S Birnbaum, W C Eastin, L Johnson and H B Matthews
    Drug Metabolism and Disposition November 1983, 11 (6) 537-543;
  • You have access
    Stereochemical composition of propranolol metabolites in the dog using stable isotope-labeled pseudoracemates.
    T Walle, M J Wilson, U K Walle and S A Bai
    Drug Metabolism and Disposition November 1983, 11 (6) 544-549;
  • You have access
    The mitochondrial metabolism of 1,2-disubstituted hydrazines, procarbazine and 1,2-dimethylhydrazine.
    M W Coomes and R A Prough
    Drug Metabolism and Disposition November 1983, 11 (6) 550-555;
  • You have access
    Effects of betamethasone on the in vitro and in vivo 2-hydroxylation of biphenyl in the rat.
    M S Miller, M T Huang, G M Williams, A M Jeffrey and A H Conney
    Drug Metabolism and Disposition November 1983, 11 (6) 556-561;
  • You have access
    Age-related changes in benzo(a)pyrene metabolism and epoxide-metabolizing enzyme activities in rat skin.
    H Mukhtar and D R Bickers
    Drug Metabolism and Disposition November 1983, 11 (6) 562-567;
  • You have access
    Isolation and characterization of metaproterenol-3-O-sulfate: a conjugate of metaproterenol in human urine.
    T R MacGregor, L Nastasi, P R Farina and J J Keirns
    Drug Metabolism and Disposition November 1983, 11 (6) 568-573;
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    Evidence for an arene-3,4-oxide as a metabolic intermediate in the meta- and para-hydroxylation of phenytoin in the dog.
    M A Moustafa, M Claesen, J Adline, D Vandervorst and J H Poupaert
    Drug Metabolism and Disposition November 1983, 11 (6) 574-580;
  • You have access
    2,2'-dihydroxy-3,3'-di-t-butyl-5,5'-dimethoxydiphenyl, a new metabolite of 2-t-butyl-4-methoxyphenol in the rat.
    A Guarna, L Della Corte, M G Giovannini, F De Sarlo and G Sgaragli
    Drug Metabolism and Disposition November 1983, 11 (6) 581-584;
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    Metabolism of ketotifen by human liver microsomes. In vitro characterization of a tertiary amine glucuronidation.
    J F Le Bigot, T Cresteil, J R Kiechel and P Beaune
    Drug Metabolism and Disposition November 1983, 11 (6) 585-589;
  • You have access
    Metabolic pathways of the topical glucocorticoid budesonide in man.
    S Edsbäcker, S Jönsson, C Lindberg, A Ryrfeldt and A Thalén
    Drug Metabolism and Disposition November 1983, 11 (6) 590-596;
  • You have access
    Disposition of 2,2',4,4',5,5'-hexachlorobiphenyl (6-CB) in rats with decreasing adipose tissue mass. II. Effects of restricting food intake before and after 6-CB administration.
    W R Jondorf, P A Wyss, S Mühlebach and M H Bickel
    Drug Metabolism and Disposition November 1983, 11 (6) 597-601;
  • You have access
    The effects of an experimental hepatitis on the metabolic disposition of 3-o-(+)-[14C]methylcatechin in the rat.
    A M Hackett and L A Griffiths
    Drug Metabolism and Disposition November 1983, 11 (6) 602-606;
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    Identification of p-hydroxyprimidone as a minor metabolite of primidone in rat and man.
    W D Hooper, A M Treston, N W Jacobsen, R G Dickinson and M J Eadie
    Drug Metabolism and Disposition November 1983, 11 (6) 607-610;
  • You have access
    Tissue disposition, metabolism, and excretion of cis- and trans-5,10-dihydrogen mirex.
    J D Yarbrough, J M Grimley, P I Karl, J E Chambers, R S Case and E G Alley
    Drug Metabolism and Disposition November 1983, 11 (6) 611-614;
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    Pulmonary absorption of drugs in the neonatal and adult guinea pig.
    J A Hemberger and L S Schanker
    Drug Metabolism and Disposition November 1983, 11 (6) 615-616;
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    Effect of urine pH on urine levels of oxyphenbutazone in racing horses.
    T Houston, T Tobin and J W Blake
    Drug Metabolism and Disposition November 1983, 11 (6) 617-619;
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    Stability of drug-metabolizing activities in lyophilized liver and lung microsomal preparations.
    J M Patel, E Ortiz, K T Shiverick and K Leibman
    Drug Metabolism and Disposition November 1983, 11 (6) 620-621;
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In this issue

Drug Metabolism and Disposition
Vol. 11, Issue 6
1 Nov 1983
  • Table of Contents
  • Index by author
  • Back Matter (PDF)
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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