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Drug Metabolism & Disposition

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Table of Contents

January 01, 1984; Volume 12,Issue 1
  • You have access
    Commentary: pharmacologic prospects of the therapeutic use of administered enzymes.
    P H Sato
    Drug Metabolism and Disposition January 1984, 12 (1) 1-3;
  • You have access
    The in vitro dechlorination of some polychlorinated ethanes.
    C Town and K C Leibman
    Drug Metabolism and Disposition January 1984, 12 (1) 4-8;
  • You have access
    Sensitive and specific determination of the new anthracycline analog 4'-epidoxorubicin and its metabolites by high pressure liquid chromatography.
    P E Deesen and B Leyland-Jones
    Drug Metabolism and Disposition January 1984, 12 (1) 9-13;
  • You have access
    Aromatization of 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline by rat liver microsomes.
    K L Fong and B Y Hwang
    Drug Metabolism and Disposition January 1984, 12 (1) 14-19;
  • You have access
    Altered biliary excretion of acetaminophen in rats fed ethanol chronically.
    G Vendemiale, E Altomare and C S Lieber
    Drug Metabolism and Disposition January 1984, 12 (1) 20-24;
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    7-ethoxycoumarin O-deethylation activity in viable basal and differentiated keratinocytes isolated from the skin of the hairless mouse.
    R J Pohl, M W Coomes, R W Sparks and J R Fouts
    Drug Metabolism and Disposition January 1984, 12 (1) 25-34;
  • You have access
    In vitro metabolism of the antimalarial agent primaquine by mouse liver enzymes and identification of a methemoglobin-forming metabolite.
    A Strother, R Allahyari, J Buchholz, I M Fraser and B E Tilton
    Drug Metabolism and Disposition January 1984, 12 (1) 35-44;
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    Metabolism of nitrotoluenes by freshly isolated Fischer 344 rat hepatocytes.
    J D deBethizy and D E Rickert
    Drug Metabolism and Disposition January 1984, 12 (1) 45-50;
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    Isolation and identification of a metabolite of rosaramicin in human urine.
    C Lin, M S Puar, D Schuessler, B N Prananik and S Symchowicz
    Drug Metabolism and Disposition January 1984, 12 (1) 51-56;
  • You have access
    A mathematical model for evaluating the reaction of paraoxon with human serum cholinesterase and with polymorphic forms of paraoxonase.
    H W Eckerson and B N La Du
    Drug Metabolism and Disposition January 1984, 12 (1) 57-62;
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    Effects of phenobarbital, 3-methylcholanthrene, and retinoid pretreatment on disposition of orally administered retinoids in mice.
    J R Kalin, M J Wells and D L Hill
    Drug Metabolism and Disposition January 1984, 12 (1) 63-67;
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    Two dihydropyrrolizine alkaloid metabolites isolated from mouse hepatic microsomes in vitro.
    H J Segall, J L Dallas and W F Haddon
    Drug Metabolism and Disposition January 1984, 12 (1) 68-71;
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    Alpha, beta-ketoalkene reduction. A novel reduction pathway in mammalian tissues.
    T D Lindstrom and G W Whitaker
    Drug Metabolism and Disposition January 1984, 12 (1) 72-76;
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    Metabolism of procainamide to a hydroxylamine by rat and human hepatic microsomes.
    J P Uetrecht, B J Sweetman, R L Woosley and J A Oates
    Drug Metabolism and Disposition January 1984, 12 (1) 77-81;
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    Fluvoxamine: metabolic fate in animals.
    H M Ruijten, H de Bree, A J Borst, N de Lange, P M Scherpenisse, W R Vincent and L C Post
    Drug Metabolism and Disposition January 1984, 12 (1) 82-92;
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    Studies of UDP-glucuronyltransferase activities in human liver microsomes.
    K W Bock, W Lilienblum and C von Bahr
    Drug Metabolism and Disposition January 1984, 12 (1) 93-97;
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    Effects of exposure concentrations on distribution of halothane metabolites in the body.
    V Fiserova-Bergerova and R W Kawiecki
    Drug Metabolism and Disposition January 1984, 12 (1) 98-105;
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    Effects of cimetidine and ranitidine on halothane metabolism and hepatotoxicity in an animal model.
    J L Plummer, S Wanwimolruk, M A Jenner, P D Hall and M J Cousins
    Drug Metabolism and Disposition January 1984, 12 (1) 106-110;
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    Identification of the glucuronide and glutathione conjugates of the antitumor drug N2-methyl-9-hydroxyellipticinium acetate (Celiptium). Comparative disposition of this drug with its olivacinium isomer in rat bile.
    M Maftouh, B Monsarrat, R C Rao, B Meunier and C Paoletti
    Drug Metabolism and Disposition January 1984, 12 (1) 111-119;
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    Disposition of cyclosporine in several animal species and man. I. Structural elucidation of its metabolites.
    G Maurer, H R Loosli, E Schreier and B Keller
    Drug Metabolism and Disposition January 1984, 12 (1) 120-126;
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    Neonatal imprinting of sex differences in the hepatic metabolism of a chlorinated cyclodiene by rat liver microsomes.
    M J Finnen and K A Hassall
    Drug Metabolism and Disposition January 1984, 12 (1) 127-130;
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    Kinetic analysis of tolbutamide-sulfonamide interaction in rabbits based on clearance concept. Prediction of species difference from in vitro plasma protein binding and metabolism.
    O Sugita, Y Sawada, Y Sugiyama, T Iga and M Hanano
    Drug Metabolism and Disposition January 1984, 12 (1) 131-138;
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    Correlation between antipyrine clearance and cytochrome P-450 level after phenobarbital induction in rat.
    S L Chang, S D Nelson and R H Levy
    Drug Metabolism and Disposition January 1984, 12 (1) 139-141;
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In this issue

Drug Metabolism and Disposition
Vol. 12, Issue 1
1 Jan 1984
  • Table of Contents
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
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  • Most Cited
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
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