Drug Metabolism and Disposition: 12 (1)

January 01, 1984; Volume 12,Issue 1

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Commentary: pharmacologic prospects of the therapeutic use of administered enzymes.
P H Sato

Drug Metabolism and Disposition January 1984, 12 (1) 1-3;
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The in vitro dechlorination of some polychlorinated ethanes.
C Town and K C Leibman

Drug Metabolism and Disposition January 1984, 12 (1) 4-8;
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Sensitive and specific determination of the new anthracycline analog 4'-epidoxorubicin and its metabolites by high pressure liquid chromatography.
P E Deesen and B Leyland-Jones

Drug Metabolism and Disposition January 1984, 12 (1) 9-13;
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Aromatization of 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline by rat liver microsomes.
K L Fong and B Y Hwang

Drug Metabolism and Disposition January 1984, 12 (1) 14-19;
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Altered biliary excretion of acetaminophen in rats fed ethanol chronically.
G Vendemiale, E Altomare and C S Lieber

Drug Metabolism and Disposition January 1984, 12 (1) 20-24;
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7-ethoxycoumarin O-deethylation activity in viable basal and differentiated keratinocytes isolated from the skin of the hairless mouse.
R J Pohl, M W Coomes, R W Sparks and J R Fouts

Drug Metabolism and Disposition January 1984, 12 (1) 25-34;
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In vitro metabolism of the antimalarial agent primaquine by mouse liver enzymes and identification of a methemoglobin-forming metabolite.
A Strother, R Allahyari, J Buchholz, I M Fraser and B E Tilton

Drug Metabolism and Disposition January 1984, 12 (1) 35-44;
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Metabolism of nitrotoluenes by freshly isolated Fischer 344 rat hepatocytes.
J D deBethizy and D E Rickert

Drug Metabolism and Disposition January 1984, 12 (1) 45-50;
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Isolation and identification of a metabolite of rosaramicin in human urine.
C Lin, M S Puar, D Schuessler, B N Prananik and S Symchowicz

Drug Metabolism and Disposition January 1984, 12 (1) 51-56;
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A mathematical model for evaluating the reaction of paraoxon with human serum cholinesterase and with polymorphic forms of paraoxonase.
H W Eckerson and B N La Du

Drug Metabolism and Disposition January 1984, 12 (1) 57-62;
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Effects of phenobarbital, 3-methylcholanthrene, and retinoid pretreatment on disposition of orally administered retinoids in mice.
J R Kalin, M J Wells and D L Hill

Drug Metabolism and Disposition January 1984, 12 (1) 63-67;
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Two dihydropyrrolizine alkaloid metabolites isolated from mouse hepatic microsomes in vitro.
H J Segall, J L Dallas and W F Haddon

Drug Metabolism and Disposition January 1984, 12 (1) 68-71;
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Alpha, beta-ketoalkene reduction. A novel reduction pathway in mammalian tissues.
T D Lindstrom and G W Whitaker

Drug Metabolism and Disposition January 1984, 12 (1) 72-76;
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Metabolism of procainamide to a hydroxylamine by rat and human hepatic microsomes.
J P Uetrecht, B J Sweetman, R L Woosley and J A Oates

Drug Metabolism and Disposition January 1984, 12 (1) 77-81;
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Fluvoxamine: metabolic fate in animals.
H M Ruijten, H de Bree, A J Borst, N de Lange, P M Scherpenisse, W R Vincent and L C Post

Drug Metabolism and Disposition January 1984, 12 (1) 82-92;
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Studies of UDP-glucuronyltransferase activities in human liver microsomes.
K W Bock, W Lilienblum and C von Bahr

Drug Metabolism and Disposition January 1984, 12 (1) 93-97;
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Effects of exposure concentrations on distribution of halothane metabolites in the body.
V Fiserova-Bergerova and R W Kawiecki

Drug Metabolism and Disposition January 1984, 12 (1) 98-105;
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Effects of cimetidine and ranitidine on halothane metabolism and hepatotoxicity in an animal model.
J L Plummer, S Wanwimolruk, M A Jenner, P D Hall and M J Cousins

Drug Metabolism and Disposition January 1984, 12 (1) 106-110;
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Identification of the glucuronide and glutathione conjugates of the antitumor drug N2-methyl-9-hydroxyellipticinium acetate (Celiptium). Comparative disposition of this drug with its olivacinium isomer in rat bile.
M Maftouh, B Monsarrat, R C Rao, B Meunier and C Paoletti

Drug Metabolism and Disposition January 1984, 12 (1) 111-119;
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Disposition of cyclosporine in several animal species and man. I. Structural elucidation of its metabolites.
G Maurer, H R Loosli, E Schreier and B Keller

Drug Metabolism and Disposition January 1984, 12 (1) 120-126;
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Neonatal imprinting of sex differences in the hepatic metabolism of a chlorinated cyclodiene by rat liver microsomes.
M J Finnen and K A Hassall

Drug Metabolism and Disposition January 1984, 12 (1) 127-130;
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Kinetic analysis of tolbutamide-sulfonamide interaction in rabbits based on clearance concept. Prediction of species difference from in vitro plasma protein binding and metabolism.
O Sugita, Y Sawada, Y Sugiyama, T Iga and M Hanano

Drug Metabolism and Disposition January 1984, 12 (1) 131-138;
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Correlation between antipyrine clearance and cytochrome P-450 level after phenobarbital induction in rat.
S L Chang, S D Nelson and R H Levy

Drug Metabolism and Disposition January 1984, 12 (1) 139-141;

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