Drug Metabolism and Disposition: 12 (3)

May 01, 1984; Volume 12,Issue 3

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Effect of L-ascorbic acid on acetaminophen-induced hepatotoxicity and covalent binding in hamsters. Evidence that in vitro covalent binding differs from that in vivo.
M G Miller and D J Jollow

Drug Metabolism and Disposition May 1984, 12 (3) 271-279;
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Identification of the metabolites of erythro-9-(2-hydroxy-3-nonyl)hypoxanthine from laboratory animals.
E H Pfadenhauer, C S Bankert, J Jensen, C E Jones, E E Jenkins and J A McCloskey

Drug Metabolism and Disposition May 1984, 12 (3) 280-284;
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Effects of salicylate on maternal and fetal phenytoin pharmacokinetics in rats.
P A Cleveland and C T Ueda

Drug Metabolism and Disposition May 1984, 12 (3) 285-290;
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Multiple reactive metabolites derived from bromobenzene.
S S Lau, T J Monks and J R Gillette

Drug Metabolism and Disposition May 1984, 12 (3) 291-296;
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Synthesis and elimination reactions of methylsulfonium ions formed from styrene oxide and methylthio compounds related to methionine and cysteine.
L S Sheng, E C Horning and M G Horning

Drug Metabolism and Disposition May 1984, 12 (3) 297-303;
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Strain and sex differences in chloroform-induced nephrotoxicity. Different rates of metabolism of chloroform to phosgene by the mouse kidney.
L R Pohl, J W George and H Satoh

Drug Metabolism and Disposition May 1984, 12 (3) 304-308;
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Disposition of enalapril and its diacid metabolite, enalaprilat, in a perfused rat liver preparation. Presence of a diffusional barrier for enalaprilat into hepatocytes.
K S Pang, W F Cherry, J A Terrell and E H Ulm

Drug Metabolism and Disposition May 1984, 12 (3) 309-313;
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Kinetics of procainamide N-acetylation in the rat in vivo and in the perfused rat liver preparation.
K S Pang, J C Huang, C Finkle, P Kong, W F Cherry and S Fayz

Drug Metabolism and Disposition May 1984, 12 (3) 314-322;
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Inhibition of acetaminophen sulfation by 2,6-dichloro-4-nitrophenol in the perfused rat liver preparation. Lack of a compensatory increase of glucuronidation.
S Fayz, W F Cherry, J R Dawson, G J Mulder and K S Pang

Drug Metabolism and Disposition May 1984, 12 (3) 323-329;
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Biotransformation of gentian violet to leucogentian violet by human, rat, and chicken intestinal microflora.
J J McDonald and C E Cerniglia

Drug Metabolism and Disposition May 1984, 12 (3) 330-336;
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N-acetylcyanamide, the major urinary metabolite of cyanamide in rat, rabbit, dog, and man.
F N Shirota, H T Nagasawa, C H Kwon and E G DeMaster

Drug Metabolism and Disposition May 1984, 12 (3) 337-344;
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N-dealkylation of propranolol in rat, dog, and man. Chemical and stereochemical aspects.
W L Nelson and M J Bartels

Drug Metabolism and Disposition May 1984, 12 (3) 345-352;
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Rapid microbial degradation of organic nitrates in rat excreta. Re-examination of the urinary and fecal metabolite profiles of pentaerythritol tetranitrate in the rat.
S Y King and H L Fung

Drug Metabolism and Disposition May 1984, 12 (3) 353-357;
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Effects of cytochrome b5 on cytochrome P-450-catalyzed reactions. Studies with manganese-substituted cytochrome b5.
E T Morgan and M J Coon

Drug Metabolism and Disposition May 1984, 12 (3) 358-364;
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The disposition of the new anthracycline antibiotic, menogarol, in mice.
P Dodion, B K Chang, M J Egorin, E A Olman, K L Engisch and N R Bachur

Drug Metabolism and Disposition May 1984, 12 (3) 365-370;
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Metabolism-dependent inactivation of liver microsomal enzymes by phencyclidine.
M K Hoag, A J Trevor, Y Asscher, J Weissman and N Castagnoli

Drug Metabolism and Disposition May 1984, 12 (3) 371-375;
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Effect of Hg2+ on accumulation and metabolism of chlorpromazine and imipramine in rat lungs.
Y Ohmiya and H M Mehendale

Drug Metabolism and Disposition May 1984, 12 (3) 376-378;
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Characterization of age-related changes in hepatic drug metabolism in miniature swine.
J O Peggins, L A Shipley and M Weiner

Drug Metabolism and Disposition May 1984, 12 (3) 379-381;
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Stereoselectivity in the aromatic hydroxylation of propranolol in the rat: use of deuterium labeling and pseudoracemic mixtures.
W L Nelson and M J Bartels

Drug Metabolism and Disposition May 1984, 12 (3) 382-384;

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